A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä

Virulence and Pathogenicity Properties of Aggregatibacter actinomycetemcomitans




TekijätBelibasakis GN, Maula T, Bao K, Lindholm M, Bostanci N, Oscarsson J, Ihalin R, Johansson A

KustantajaMDPI

Julkaisuvuosi2019

JournalPathogens

Tietokannassa oleva lehden nimiPathogens (Basel, Switzerland)

Lehden akronyymiPathogens

Artikkelin numeroE222

Vuosikerta8

Numero4

Sivujen määrä23

ISSN2076-0817

eISSN2076-0817

DOIhttps://doi.org/10.3390/pathogens8040222

Verkko-osoitehttps://www.mdpi.com/2076-0817/8/4/222

Rinnakkaistallenteen osoitehttps://research.utu.fi/converis/portal/detail/Publication/42910627


Tiivistelmä
Aggregatibacter actinomycetemcomitans is a periodontal pathogen
colonizing the oral cavity of a large proportion of the human
population. It is equipped with several potent virulence factors that
can cause cell death and induce or evade inflammation. Because of the
large genetic diversity within the species, both harmless and highly
virulent genotypes of the bacterium have emerged. The oral condition and
age, as well as the geographic origin of the individual, influence the
risk to be colonized by a virulent genotype of the bacterium. In the
present review, the virulence and pathogenicity properties of A. actinomycetemcomitans will be addressed.

Ladattava julkaisu

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Last updated on 2024-26-11 at 18:12