A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä

Close-loop dynamic nanohybrids on collagen-ark with in situ gelling transformation capability for biomimetic stage-specific diabetic wound healing




TekijätZehua Liu, Yunzhan Li, Wei Li, Wenhua Lian, Marianna Kemell, Sami Hietala, Patrícia Figueiredo, Li Li, Ermei Mäkilä, Ming Ma, Jarno Salonen, Jouni T. Hirvonen, Dongfei Liu, Hongbo Zhang, Xianming Deng, Hélder A. Santos

KustantajaROYAL SOC CHEMISTRY

Julkaisuvuosi2019

JournalMaterials Horizons

Tietokannassa oleva lehden nimiMATERIALS HORIZONS

Lehden akronyymiMATER HORIZ

Vuosikerta6

Numero2

Aloitussivu385

Lopetussivu393

Sivujen määrä9

ISSN2051-6347

DOIhttps://doi.org/10.1039/c8mh01145a

Verkko-osoitehttps://pubs.rsc.org/en/Content/ArticleLanding/2019/MH/C8MH01145A#!divAbstract

Rinnakkaistallenteen osoitehttps://research.utu.fi/converis/portal/detail/Publication/39807705


Tiivistelmä
Here, an oxidation/acid dual-responsive nanohybrids/ark system was produced. The microfluidics-produced nanohybrids endow the system with an orchestrated cascade from wound detection, reactive oxygen species scavenging, drug release to hydrogel formation. The drug release behavior imitates the dynamic wound healing process, thus rendering an enhanced bio-mimetic regeneration.

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Last updated on 2024-26-11 at 13:40