A4 Refereed article in a conference publication

Resolution Transfer in Cancer Classification Based on Amplification Patterns




AuthorsAdhikari Prem Raj, Hollmén Jaakko

EditorsNathalie Japkowicz, Stan Matwin

Conference nameInternational Conference on Discovery Science

Publication year2015

Journal:Lecture Notes in Computer Science

Book title Discovery Science: 18th International Conference, DS 2015, Banff, AB, Canada, October 4-6, 2015. Proceedings

Series titleLecture Notes in Computer Science

Volume9356

First page 1

Last page8

Number of pages8

ISBN978-3-319-24281-1

ISSN0302-9743

DOIhttps://doi.org/10.1007/978-3-319-24282-8_1

Self-archived copy’s web addresshttps://research.utu.fi/converis/portal/detail/Publication/3890358


Abstract

In the current scientific age, the measurement technology has considerably improved and diversified producing data in different representations. Traditional machine learning and data mining algorithms can handle data only in a single representation in their standard form. In this contribution, we address an important challenge encountered in data analysis: what to do when the data to be analyzed are represented differently with regards to the resolution? Specifically, in classification, how to train a classifier when class labels are available only in one resolution and missing in the other resolutions? The proposed methodology learns a classifier in one data resolution and transfers it to learn the class labels in a different resolution. Furthermore, the methodology intuitively works as a dimensionality reduction method. The methodology is evaluated on a simulated dataset and finally used to classify cancers in a real–world multiresolution chromosomal aberration dataset producing plausible results.


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