Biotechnological challenges of phage therapy



: Skurnik M, Pajunen M, Kiljunen S

Publisher: SPRINGER

: 2007

 Biotechnology Letters

: BIOTECHNOLOGY LETTERS

: BIOTECHNOL LETT

: 29

: 7

: 995

: 1003

: 9

: 0141-5492

DOI: https://doi.org/10.1007/s10529-007-9346-1


The challenges for successful launching of a profitable phage therapeutic product include intellectual property rights, safety issues, reproducibility, stability and robustness of the product. A successful and marketable product would be a highly purified bacteriophage preparation containing one or several fully characterized phages, accompanied by optimized methods of administration and backed up by properly controlled efficacy and safety studies.


bacteriophage, gene, sequence, therapy, toxin, virulence factor



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