A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Biotechnological challenges of phage therapy
Tekijät: Skurnik M, Pajunen M, Kiljunen S
Kustantaja: SPRINGER
Julkaisuvuosi: 2007
Lehti:: Biotechnology Letters
Tietokannassa oleva lehden nimi: BIOTECHNOLOGY LETTERS
Lehden akronyymi: BIOTECHNOL LETT
Vuosikerta: 29
Numero: 7
Aloitussivu: 995
Lopetussivu: 1003
Sivujen määrä: 9
ISSN: 0141-5492
DOI: https://doi.org/10.1007/s10529-007-9346-1
Tiivistelmä
The challenges for successful launching of a profitable phage therapeutic product include intellectual property rights, safety issues, reproducibility, stability and robustness of the product. A successful and marketable product would be a highly purified bacteriophage preparation containing one or several fully characterized phages, accompanied by optimized methods of administration and backed up by properly controlled efficacy and safety studies.
The challenges for successful launching of a profitable phage therapeutic product include intellectual property rights, safety issues, reproducibility, stability and robustness of the product. A successful and marketable product would be a highly purified bacteriophage preparation containing one or several fully characterized phages, accompanied by optimized methods of administration and backed up by properly controlled efficacy and safety studies.