A1 Refereed original research article in a scientific journal
Biotechnological challenges of phage therapy
Authors: Skurnik M, Pajunen M, Kiljunen S
Publisher: SPRINGER
Publication year: 2007
Journal: Biotechnology Letters
Journal name in source: BIOTECHNOLOGY LETTERS
Journal acronym: BIOTECHNOL LETT
Volume: 29
Issue: 7
First page : 995
Last page: 1003
Number of pages: 9
ISSN: 0141-5492
DOI: https://doi.org/10.1007/s10529-007-9346-1
Abstract
The challenges for successful launching of a profitable phage therapeutic product include intellectual property rights, safety issues, reproducibility, stability and robustness of the product. A successful and marketable product would be a highly purified bacteriophage preparation containing one or several fully characterized phages, accompanied by optimized methods of administration and backed up by properly controlled efficacy and safety studies.
The challenges for successful launching of a profitable phage therapeutic product include intellectual property rights, safety issues, reproducibility, stability and robustness of the product. A successful and marketable product would be a highly purified bacteriophage preparation containing one or several fully characterized phages, accompanied by optimized methods of administration and backed up by properly controlled efficacy and safety studies.
Keywords:
bacteriophage, gene, sequence, therapy, toxin, virulence factor
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