B1 Vertaisarvioimaton kirjoitus tieteellisessä lehdessä
A scientific debate: The sword that cleaves chaos of DNAzyme catalysis research
Tekijät: Yan Jiaqi, Ran Meixin, Zhang Hongbo
Kustantaja: Publishing services by Elsevier on behalf of KeAi Communications
Julkaisuvuosi: 2023
Journal: Biomedical Technology
Tietokannassa oleva lehden nimi: Biomedical Technology
Vuosikerta: 4
Aloitussivu: 21
Lopetussivu: 23
eISSN: 2949-723X
DOI: https://doi.org/10.1016/j.bmt.2023.01.004
Verkko-osoite: https://doi.org/10.1016/j.bmt.2023.01.004
Rinnakkaistallenteen osoite: https://research.utu.fi/converis/portal/detail/Publication/381245251
Therapeutic DNAzymes with RNA depleting effect are multifunctional building blocks for constructing biological materials. In a recent work published in Nature Chemistry, Holliger group and Chaput group had a wonderful debate base on previously reported approach for tailoring DNAzymes with high mRNA cleavage activity in mammalian cells. Their perspective pushes the catalytic mechanism investigation of DNAzymes to a new stage with more standardization and clarity.
Ladattava julkaisu This is an electronic reprint of the original article. |  |
