The vacuole versus the lysosome When size matters

: Klionsky DJ, Eskelinen EL

Publisher: LANDES BIOSCIENCE

: 2014

: Autophagy

: AUTOPHAGY

: 10

: 2

: 185

: 187

: 3

: 1554-8627

DOI: https://doi.org/10.4161/auto.27367

The morphometric examination of autophagic bodies provides useful information about the mechanism and magnitude of macroautophagy, and yeast researchers frequently utilize various measurements of these structures as part of their quantification of the process. The utility of this approach, however, has led to the common misconception that autophagic bodies can be found in the mammalian lysosome, which is generally not correct.