A1 Refereed original research article in a scientific journal
The vacuole versus the lysosome When size matters
Authors: Klionsky DJ, Eskelinen EL
Publisher: LANDES BIOSCIENCE
Publication year: 2014
Journal: Autophagy
Journal name in source: AUTOPHAGY
Journal acronym: AUTOPHAGY
Volume: 10
Issue: 2
First page : 185
Last page: 187
Number of pages: 3
ISSN: 1554-8627
DOI: https://doi.org/10.4161/auto.27367
Abstract
The morphometric examination of autophagic bodies provides useful information about the mechanism and magnitude of macroautophagy, and yeast researchers frequently utilize various measurements of these structures as part of their quantification of the process. The utility of this approach, however, has led to the common misconception that autophagic bodies can be found in the mammalian lysosome, which is generally not correct.
The morphometric examination of autophagic bodies provides useful information about the mechanism and magnitude of macroautophagy, and yeast researchers frequently utilize various measurements of these structures as part of their quantification of the process. The utility of this approach, however, has led to the common misconception that autophagic bodies can be found in the mammalian lysosome, which is generally not correct.