A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
The vacuole versus the lysosome When size matters
Tekijät: Klionsky DJ, Eskelinen EL
Kustantaja: LANDES BIOSCIENCE
Julkaisuvuosi: 2014
Journal: Autophagy
Tietokannassa oleva lehden nimi: AUTOPHAGY
Lehden akronyymi: AUTOPHAGY
Vuosikerta: 10
Numero: 2
Aloitussivu: 185
Lopetussivu: 187
Sivujen määrä: 3
ISSN: 1554-8627
DOI: https://doi.org/10.4161/auto.27367
Tiivistelmä
The morphometric examination of autophagic bodies provides useful information about the mechanism and magnitude of macroautophagy, and yeast researchers frequently utilize various measurements of these structures as part of their quantification of the process. The utility of this approach, however, has led to the common misconception that autophagic bodies can be found in the mammalian lysosome, which is generally not correct.
The morphometric examination of autophagic bodies provides useful information about the mechanism and magnitude of macroautophagy, and yeast researchers frequently utilize various measurements of these structures as part of their quantification of the process. The utility of this approach, however, has led to the common misconception that autophagic bodies can be found in the mammalian lysosome, which is generally not correct.