A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Post-target produced [18F]F2 in the production of PET radiopharmaceuticals.
Tekijät: Forsback S, Solin O
Kustantaja: De Gruyter
Julkaisuvuosi: 2015
Journal: Radiochimica Acta
Lehden akronyymi: Radiochim acta
Vuosikerta: 103
Numero: 3
Aloitussivu: 219
Lopetussivu: 226
Sivujen määrä: 8
ISSN: 0033-8230
DOI: https://doi.org/10.1515/ract-2014-2334
Rinnakkaistallenteen osoite: https://research.utu.fi/converis/portal/detail/Publication/3433612
Electrophilic radiofluorination was successfully carried out in the early years of PET radiochemistry due to its ease and fast reaction speed. However, at the present, the use of electrophilic methods is limited due to low specific activity (SA). Post-target produced [F-18]F-2 has significantly higher SA compared to other electrophilic approaches, and it has been used in the production of clinical PET radiopharmaceuticals at the Turku PET Centre for years. Here, we summarize the synthesis and use of these radiopharmaceuticals, namely [F-18]FDOPA, [F-18]CFT, [F-18]EF5 and [F-18]FBPA.
Ladattava julkaisu This is an electronic reprint of the original article. |  |
