Intrahepatic cholestasis of pregnancy: observational study of the treatment with low-dose ursodeoxycholic acid




Joutsiniemi T, Timonen S, Linden M, Suvitie P, Ekblad U

PublisherBIOMED CENTRAL LTD

2015

BMC Gastroenterology

BMC GASTROENTEROLOGY

BMC GASTROENTEROL

ARTN 92

15

7

1471-230X

DOIhttps://doi.org/10.1186/s12876-015-0324-0



Conclusions: Preterm labour was associated in severe ICP (total BA > 40 mu mol/l), ALT levels were also significantly higher and ICP was diagnosed earlier (p < 0.05). Apgar scores were lower in preterm babies (p < 0.05), but umbilical artery pHvalues were not significantly lower. UDCA was well tolerated by pregnant women. With low-dose UDCA treatment the obstetric outcome was good. We still recommend careful obstetrical follow-up.




Last updated on 2024-26-11 at 23:23