Global expression of AMACR transcripts predicts risk for prostate cancer - a systematic comparison of AMACR protein and mRNA expression in cancerous and noncancerous prostate



: Alinezhad S, Vaananen RM, Ochoa NT, Vertosick EA, Bjartell A, Bostrom PJ, Taimen P, Pettersson K

Publisher: BIOMED CENTRAL LTD

: 2016

: BMC Urology

: BMC UROLOGY

: BMC UROL

: ARTN 10

: 16

: 10

: 1471-2490

DOI: https://doi.org/10.1186/s12894-016-0128-8


Conclusions: AMACR transcripts were detected in all RP-PCa and RP-Be samples but not in non-cancerous CP samples, which suggest a global increase of AMACR expression in cancerous prostates. Therefore patients with false negative biopsies might benefit from an AMACR mRNA measurement when assessing their cancer risk.



Last updated on 2024-26-11 at 22:22