Interleukin-6 gene polymorphism, chronic stress and atherosclerosis Interleukin-6-174G>C polymorphism, chronic stress and risk of early atherosclerosis in the Cardiovascular Risk in Young Finns Study



: Chumaeva N, Hintsanen M, Pulkki-Raback L, Jokela M, Juonala M, Lehtimaki T, Raitakari OT, Keltikangas-Jarvinen L

Publisher: PERGAMON-ELSEVIER SCIENCE LTD

: 2014

: Journal of Psychosomatic Research

: JOURNAL OF PSYCHOSOMATIC RESEARCH

: J PSYCHOSOM RES

: 76

: 4

: 333

: 338

: 6

: 0022-3999

DOI: https://doi.org/10.1016/j.jpsychores.2014.01.007


Conclusion: Our findings support a role for the interleukin-6-174G>C polymorphism in increased risk of atherosclerosis in individuals with chronic stress. In addition, individuals carrying the G allele of the interleukin-6-174G>C polymorphism may be more prone to adverse effects of psychosocial stress. (C) 2014 Elsevier Inc. All rights reserved.



Last updated on 2024-26-11 at 13:07