A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Interleukin-6 gene polymorphism, chronic stress and atherosclerosis Interleukin-6-174G>C polymorphism, chronic stress and risk of early atherosclerosis in the Cardiovascular Risk in Young Finns Study
Tekijät: Chumaeva N, Hintsanen M, Pulkki-Raback L, Jokela M, Juonala M, Lehtimaki T, Raitakari OT, Keltikangas-Jarvinen L
Kustantaja: PERGAMON-ELSEVIER SCIENCE LTD
Julkaisuvuosi: 2014
Journal: Journal of Psychosomatic Research
Tietokannassa oleva lehden nimi: JOURNAL OF PSYCHOSOMATIC RESEARCH
Lehden akronyymi: J PSYCHOSOM RES
Vuosikerta: 76
Numero: 4
Aloitussivu: 333
Lopetussivu: 338
Sivujen määrä: 6
ISSN: 0022-3999
DOI: https://doi.org/10.1016/j.jpsychores.2014.01.007
Tiivistelmä
Conclusion: Our findings support a role for the interleukin-6-174G>C polymorphism in increased risk of atherosclerosis in individuals with chronic stress. In addition, individuals carrying the G allele of the interleukin-6-174G>C polymorphism may be more prone to adverse effects of psychosocial stress. (C) 2014 Elsevier Inc. All rights reserved.
Conclusion: Our findings support a role for the interleukin-6-174G>C polymorphism in increased risk of atherosclerosis in individuals with chronic stress. In addition, individuals carrying the G allele of the interleukin-6-174G>C polymorphism may be more prone to adverse effects of psychosocial stress. (C) 2014 Elsevier Inc. All rights reserved.