A1 Refereed original research article in a scientific journal

Interleukin-6 gene polymorphism, chronic stress and atherosclerosis Interleukin-6-174G>C polymorphism, chronic stress and risk of early atherosclerosis in the Cardiovascular Risk in Young Finns Study



Authors: Chumaeva N, Hintsanen M, Pulkki-Raback L, Jokela M, Juonala M, Lehtimaki T, Raitakari OT, Keltikangas-Jarvinen L

Publisher: PERGAMON-ELSEVIER SCIENCE LTD

Publication year: 2014

Journal: Journal of Psychosomatic Research

Journal name in source: JOURNAL OF PSYCHOSOMATIC RESEARCH

Journal acronym: J PSYCHOSOM RES

Volume: 76

Issue: 4

First page : 333

Last page: 338

Number of pages: 6

ISSN: 0022-3999

DOI: https://doi.org/10.1016/j.jpsychores.2014.01.007


Abstract
Conclusion: Our findings support a role for the interleukin-6-174G>C polymorphism in increased risk of atherosclerosis in individuals with chronic stress. In addition, individuals carrying the G allele of the interleukin-6-174G>C polymorphism may be more prone to adverse effects of psychosocial stress. (C) 2014 Elsevier Inc. All rights reserved.



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