Accurate detection of differential expression and splicing using low-level features



: Suomi Tomi, Elo Laura L

: Wajapeyee Narendra, Gupta Romi

: 1

Publisher: HUMANA PRESS INC, 999 RIVERVIEW DR, STE 208, TOTOWA, NJ 07512-1165 USA

: New York

: 2017

: Methods in Molecular Biology

: Eukaryotic transcriptional and post-transcriptional gene expression regulation

: EUKARYOTIC TRANSCRIPTIONAL AND POST-TRANSCRIPTIONAL GENE EXPRESSION REGULATION

: METHODS MOL BIOL

: Methods in Molecular Biology

: 1507

: 141

: 151

: 11

: 978-1-4939-6516-8

: 978-1-4939-6518-2

: 1064-3745

DOI: https://doi.org/10.1007/978-1-4939-6518-2_11(external)


Gene expression can be quantified in high throughput using microarray technology. Here we describe how to accurately detect differential expression and splicing using a probe-level expression change averaging (PECA) method. PECA is available as an R package from Bioconductor (https://www.bioconductor.org), and it supports multiple operating systems.



Last updated on 2024-26-11 at 23:22