A3 Refereed book chapter or chapter in a compilation book
Accurate detection of differential expression and splicing using low-level features
Authors: Suomi Tomi, Elo Laura L
Editors: Wajapeyee Narendra, Gupta Romi
Edition: 1
Publisher: HUMANA PRESS INC, 999 RIVERVIEW DR, STE 208, TOTOWA, NJ 07512-1165 USA
Publishing place: New York
Publication year: 2017
Journal: Methods in Molecular Biology
Book title : Eukaryotic transcriptional and post-transcriptional gene expression regulation
Journal name in source: EUKARYOTIC TRANSCRIPTIONAL AND POST-TRANSCRIPTIONAL GENE EXPRESSION REGULATION
Journal acronym: METHODS MOL BIOL
Series title: Methods in Molecular Biology
Volume: 1507
First page : 141
Last page: 151
Number of pages: 11
ISBN: 978-1-4939-6516-8
eISBN: 978-1-4939-6518-2
ISSN: 1064-3745
DOI: https://doi.org/10.1007/978-1-4939-6518-2_11
Gene expression can be quantified in high throughput using microarray technology. Here we describe how to accurately detect differential expression and splicing using a probe-level expression change averaging (PECA) method. PECA is available as an R package from Bioconductor (https://www.bioconductor.org), and it supports multiple operating systems.
