Prevalence of Concomitant Use of Alcohol and Sedative-Hypnotic Drugs in Middle and Older Aged Persons: A Systematic Review



: Ilomaki J, Paljarvi T, Korhonen MJ, Enlund H, Alderman CP, Kauhanen J, Bell JS

Publisher: SAGE PUBLICATIONS INC

: 2013

: Annals of Pharmacotherapy

: ANNALS OF PHARMACOTHERAPY

: ANN PHARMACOTHER

: 2

: 47

: 2

: 257

: 268

: 12

: 1060-0280

DOI: https://doi.org/10.1345/aph.1R449


CONCLUSIONS: Our review identified a higher prevalence of alcohol consumption among middle-aged than older persons. However, middle-aged persons may experience harm from alcohol/sedative-hypnotic drug interactions due to risky drinking behavior. Despite lower levels of alcohol consumption, older persons may be more susceptible to addictive central nervous system effects than younger persons because of physiologic changes in psychotropic drug and alcohol metabolism. Clinicians should consider patients' alcohol consumption patterns before prescribing sedative-hypnotic drugs.



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