A2 Refereed review article in a scientific journal
Prevalence of Concomitant Use of Alcohol and Sedative-Hypnotic Drugs in Middle and Older Aged Persons: A Systematic Review
Authors: Ilomaki J, Paljarvi T, Korhonen MJ, Enlund H, Alderman CP, Kauhanen J, Bell JS
Publisher: SAGE PUBLICATIONS INC
Publication year: 2013
Journal: Annals of Pharmacotherapy
Journal name in source: ANNALS OF PHARMACOTHERAPY
Journal acronym: ANN PHARMACOTHER
Number in series: 2
Volume: 47
Issue: 2
First page : 257
Last page: 268
Number of pages: 12
ISSN: 1060-0280
DOI: https://doi.org/10.1345/aph.1R449
Abstract
CONCLUSIONS: Our review identified a higher prevalence of alcohol consumption among middle-aged than older persons. However, middle-aged persons may experience harm from alcohol/sedative-hypnotic drug interactions due to risky drinking behavior. Despite lower levels of alcohol consumption, older persons may be more susceptible to addictive central nervous system effects than younger persons because of physiologic changes in psychotropic drug and alcohol metabolism. Clinicians should consider patients' alcohol consumption patterns before prescribing sedative-hypnotic drugs.
CONCLUSIONS: Our review identified a higher prevalence of alcohol consumption among middle-aged than older persons. However, middle-aged persons may experience harm from alcohol/sedative-hypnotic drug interactions due to risky drinking behavior. Despite lower levels of alcohol consumption, older persons may be more susceptible to addictive central nervous system effects than younger persons because of physiologic changes in psychotropic drug and alcohol metabolism. Clinicians should consider patients' alcohol consumption patterns before prescribing sedative-hypnotic drugs.
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