A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä
Prevalence of Concomitant Use of Alcohol and Sedative-Hypnotic Drugs in Middle and Older Aged Persons: A Systematic Review
Tekijät: Ilomaki J, Paljarvi T, Korhonen MJ, Enlund H, Alderman CP, Kauhanen J, Bell JS
Kustantaja: SAGE PUBLICATIONS INC
Julkaisuvuosi: 2013
Lehti: Annals of Pharmacotherapy
Tietokannassa oleva lehden nimi: ANNALS OF PHARMACOTHERAPY
Lehden akronyymi: ANN PHARMACOTHER
Numero sarjassa: 2
Vuosikerta: 47
Numero: 2
Aloitussivu: 257
Lopetussivu: 268
Sivujen määrä: 12
ISSN: 1060-0280
DOI: https://doi.org/10.1345/aph.1R449
Tiivistelmä
CONCLUSIONS: Our review identified a higher prevalence of alcohol consumption among middle-aged than older persons. However, middle-aged persons may experience harm from alcohol/sedative-hypnotic drug interactions due to risky drinking behavior. Despite lower levels of alcohol consumption, older persons may be more susceptible to addictive central nervous system effects than younger persons because of physiologic changes in psychotropic drug and alcohol metabolism. Clinicians should consider patients' alcohol consumption patterns before prescribing sedative-hypnotic drugs.
CONCLUSIONS: Our review identified a higher prevalence of alcohol consumption among middle-aged than older persons. However, middle-aged persons may experience harm from alcohol/sedative-hypnotic drug interactions due to risky drinking behavior. Despite lower levels of alcohol consumption, older persons may be more susceptible to addictive central nervous system effects than younger persons because of physiologic changes in psychotropic drug and alcohol metabolism. Clinicians should consider patients' alcohol consumption patterns before prescribing sedative-hypnotic drugs.
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