Biomimetic Engineering Using Cancer Cell Membranes for Designing Compartmentalized Nanoreactors with Organelle-Like Functions



: Vimalkumar Balasubramanian, Alexandra Correia, Hongbo Zhang, Flavia Fontana, Ermei Mäkilä, Jarno Salonen, Jouni Hirvonen, Helder A. Santos

Publisher: WILEY-V C H VERLAG GMBH

: 2017

 Advanced Materials

: ADVANCED MATERIALS

: ADV MATER

: UNSP 1605375

: 29

: 11

: 8

: 0935-9648

: 1521-4095

DOI: https://doi.org/10.1002/adma.201605375


A new biomimetic nanoreactor design is presented based on cancer cell membrane material in combination with porous silicon nanoparticles. This cellular nanoreactor features a biocompartment enclosed by a cell membrane and readily integrated with cells and supplementing the cellular functions under oxidative stress. The study demonstrates the impact of the nanoreactors on improving cellular functions with a potential to serve as artificial organelles.



Last updated on 26/11/2024 11:52:27 PM