A1 Refereed original research article in a scientific journal
Biomimetic Engineering Using Cancer Cell Membranes for Designing Compartmentalized Nanoreactors with Organelle-Like Functions
Authors: Vimalkumar Balasubramanian, Alexandra Correia, Hongbo Zhang, Flavia Fontana, Ermei Mäkilä, Jarno Salonen, Jouni Hirvonen, Helder A. Santos
Publisher: WILEY-V C H VERLAG GMBH
Publication year: 2017
Journal: Advanced Materials
Journal name in source: ADVANCED MATERIALS
Journal acronym: ADV MATER
Article number: UNSP 1605375
Volume: 29
Issue: 11
Number of pages: 8
ISSN: 0935-9648
eISSN: 1521-4095
DOI: https://doi.org/10.1002/adma.201605375
Abstract
A new biomimetic nanoreactor design is presented based on cancer cell membrane material in combination with porous silicon nanoparticles. This cellular nanoreactor features a biocompartment enclosed by a cell membrane and readily integrated with cells and supplementing the cellular functions under oxidative stress. The study demonstrates the impact of the nanoreactors on improving cellular functions with a potential to serve as artificial organelles.
A new biomimetic nanoreactor design is presented based on cancer cell membrane material in combination with porous silicon nanoparticles. This cellular nanoreactor features a biocompartment enclosed by a cell membrane and readily integrated with cells and supplementing the cellular functions under oxidative stress. The study demonstrates the impact of the nanoreactors on improving cellular functions with a potential to serve as artificial organelles.
UTU Research Portal