A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Biomimetic Engineering Using Cancer Cell Membranes for Designing Compartmentalized Nanoreactors with Organelle-Like Functions
Tekijät: Vimalkumar Balasubramanian, Alexandra Correia, Hongbo Zhang, Flavia Fontana, Ermei Mäkilä, Jarno Salonen, Jouni Hirvonen, Helder A. Santos
Kustantaja: WILEY-V C H VERLAG GMBH
Julkaisuvuosi: 2017
Lehti: Advanced Materials
Tietokannassa oleva lehden nimi: ADVANCED MATERIALS
Lehden akronyymi: ADV MATER
Artikkelin numero: UNSP 1605375
Vuosikerta: 29
Numero: 11
Sivujen määrä: 8
ISSN: 0935-9648
eISSN: 1521-4095
DOI: https://doi.org/10.1002/adma.201605375
Tiivistelmä
A new biomimetic nanoreactor design is presented based on cancer cell membrane material in combination with porous silicon nanoparticles. This cellular nanoreactor features a biocompartment enclosed by a cell membrane and readily integrated with cells and supplementing the cellular functions under oxidative stress. The study demonstrates the impact of the nanoreactors on improving cellular functions with a potential to serve as artificial organelles.
A new biomimetic nanoreactor design is presented based on cancer cell membrane material in combination with porous silicon nanoparticles. This cellular nanoreactor features a biocompartment enclosed by a cell membrane and readily integrated with cells and supplementing the cellular functions under oxidative stress. The study demonstrates the impact of the nanoreactors on improving cellular functions with a potential to serve as artificial organelles.
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