A3 Vertaisarvioitu kirjan tai muun kokoomateoksen osa
Genetic, molecular, and cellular determinations of sex-specific cardiovascular traits
Tekijät: Vaura Felix
Toimittaja: Marianne J. Legato, Dov Feldberg, Marek Glezerman
Kustantaja: Elsevier
Julkaisuvuosi: 2023
Kokoomateoksen nimi: Sex, Gender, and Epigenetics: From Molecule to Bedside
Tietokannassa oleva lehden nimi: Sex, Gender, and Epigenetics: From Molecule to Bedside
Aloitussivu: 35
Lopetussivu: 46
ISBN: 978-0-12-823937-7
DOI: https://doi.org/10.1016/B978-0-12-823937-7.00020-1
Verkko-osoite: https://www.sciencedirect.com/science/article/abs/pii/B9780128239377000201?via%3Dihub
Cardiovascular disease, the number one killer worldwide, affects men and women differently. This chapter explores how sex modifies the effect of subcellular information carriers—sex hormones, the transcriptome, the epigenome, and the genome—on cardiovascular traits and outcomes. The emphasis will be on human studies, particularly those that report sex-specific associations between the epigenome and the cardiovascular system.
