A3 Refereed book chapter or chapter in a compilation book
Genetic, molecular, and cellular determinations of sex-specific cardiovascular traits
Authors: Vaura Felix
Editors: Marianne J. Legato, Dov Feldberg, Marek Glezerman
Publisher: Elsevier
Publication year: 2023
Book title : Sex, Gender, and Epigenetics: From Molecule to Bedside
Journal name in source: Sex, Gender, and Epigenetics: From Molecule to Bedside
First page : 35
Last page: 46
ISBN: 978-0-12-823937-7
DOI: https://doi.org/10.1016/B978-0-12-823937-7.00020-1
Web address : https://www.sciencedirect.com/science/article/abs/pii/B9780128239377000201?via%3Dihub
Cardiovascular disease, the number one killer worldwide, affects men and women differently. This chapter explores how sex modifies the effect of subcellular information carriers—sex hormones, the transcriptome, the epigenome, and the genome—on cardiovascular traits and outcomes. The emphasis will be on human studies, particularly those that report sex-specific associations between the epigenome and the cardiovascular system.
