Porous 316L stainless steel samples were functionalized with electrodeposited zinc, copper, and silver coatings for antimicrobial activity against gram-positive bacteria Staphylococcus aureus (S. aureus). Porous stainless steel samples were created by combining metal injection molding (MIM) with a powder space holder (PSH) technique using sodium chloride (20 wt%) as a space holder material. Galvanostatic (0.10 A) electrodeposition was used for zinc, copper, and silver deposition, and antimicrobial activity of functionalized samples was evaluated using a touch test protocol with S. aureus. All electrodeposited samples completely prevented the growth of S. aureus. These results confirm that metal depositions only in the pores of the porous 316L were sufficient to inhibit the growth of S. aureus completely.