A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Finnish children carrying the high-risk HLA genotype have a 45-fold increased risk of type 1 diabetes compared to peers with neutral or protective genotypes
Tekijät: Taka Antti-Mathias, But Anna, Lempainen Johanna, Vatanen Tommi, Härkönen Taina, Ilonen Jorma, Knip Mikael
Kustantaja: Elsevier
Julkaisuvuosi: 2023
Journal: Diabetes Research and Clinical Practice
Tietokannassa oleva lehden nimi: Diabetes research and clinical practice
Lehden akronyymi: Diabetes Res Clin Pract
Artikkelin numero: 110256
Vuosikerta: 197
ISSN: 0168-8227
eISSN: 1872-8227
DOI: https://doi.org/10.1016/j.diabres.2023.110256
Verkko-osoite: https://doi.org/10.1016/j.diabres.2023.110256
Rinnakkaistallenteen osoite: https://research.utu.fi/converis/portal/detail/Publication/179032396
The association between HLA genotypes and type 1 diabetes is well known. We set out to examine incidence rates and ratios of type 1 diabetes depending on the risk afflicted by HLA genotype. Children with the high-risk genotype have a 45-fold disease risk compared to peers with neutral or protective genotypes.
Ladattava julkaisu This is an electronic reprint of the original article. |