A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Cell type markers indicate distinct contributions of decidual stromal cells and natural killer cells in preeclampsia
Tekijät: Rytkönen Kalle T, Adossa Nigatu, Mahmoudian Mehrad, Lönnberg Tapio, Poutanen Matti, Elo Laura L
Kustantaja: BIOSCIENTIFICA LTD
Julkaisuvuosi: 2022
Journal: Reproduction
Tietokannassa oleva lehden nimi: REPRODUCTION
Lehden akronyymi: REPRODUCTION
Vuosikerta: 164
Numero: 5
Aloitussivu: V9
Lopetussivu: V13
Sivujen määrä: 5
ISSN: 1470-1626
eISSN: 1741-7899
DOI: https://doi.org/10.1530/REP-22-0079
Verkko-osoite: http://dx.doi.org/10.1530%2FREP-22-0079
Rinnakkaistallenteen osoite: https://research.utu.fi/converis/portal/detail/Publication/178040409
In brief: Preeclampsia is a common serious disorder that can occur during pregnancy. This study uses integrative analysis of preeclampsia transcriptomes and single-cell transcriptomes to predict cell type-specific contributions to preeclampsia. Preeclampsia is a devastating pregnancy disorder and a major cause of maternal and perinatal mortality. By combining previous transcriptomic results on preeclampsia with single-cell sequencing data, we here predict distinct and partly unanticipated contributions of decidual stromal cells and uterine natural killer cells in early- and late-onset preeclampsia.
Ladattava julkaisu This is an electronic reprint of the original article. |  |
