Refereed review article in scientific journal (A2)
Sperm, metabolic memory and echoes from Lamarck
List of Authors: Crisostomo L, Oliveira PF, Alves MG
Publisher: WILEY
Publication year: 2021
Journal: European Journal of Clinical Investigation
Journal name in source: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
Journal acronym: EUR J CLIN INVEST
Volume number: 51
Issue number: 10
Number of pages: 5
ISSN: 0014-2972
DOI: http://dx.doi.org/10.1111/eci.13492
URL: https://onlinelibrary.wiley.com/doi/10.1111/eci.13492
Abstract
- There is a widespread misconception that only maternal variables affect in utero development.
- Epigenetic markers carried by the spermatozoon are transmitted to the zygote.
- Sperm-born epigenetic factors influence in utero development, for various generations.
- Acquired traits of metabolic disease can be inherited by the offspring via the male gamete.
- Health assessment of future fathers is essential to predict the offspring's health.
Downloadable publication This is an electronic reprint of the original article. |