A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Schizophrenia polygenic risk score and long-term success in the labour market: A cohort study
Tekijät: Viinikainen Jutta, Böckerman Petri, Hakulinen Christian, Kari Jaana T, Lehtimäki Terho, Raitakari Olli T, Pehkonen Jaakko
Kustantaja: PERGAMON-ELSEVIER SCIENCE LTD
Julkaisuvuosi: 2022
Journal: Journal of Psychiatric Research
Tietokannassa oleva lehden nimi: JOURNAL OF PSYCHIATRIC RESEARCH
Lehden akronyymi: J PSYCHIATR RES
Vuosikerta: 151
Aloitussivu: 638
Lopetussivu: 641
Sivujen määrä: 4
ISSN: 0022-3956
eISSN: 1879-1379
DOI: https://doi.org/10.1016/j.jpsychires.2022.05.041
Verkko-osoite: https://www.sciencedirect.com/science/article/pii/S0022395622002941
Rinnakkaistallenteen osoite: https://research.utu.fi/converis/portal/detail/Publication/175741642
Employment is rare among people with a schizophrenia diagnosis. Meanwhile, a genetic liability for schizophrenia may hinder labour market performance. We studied how the polygenic risk score (PGS) for schizophrenia related to education and labour market outcomes. We found that a higher PGS was linked to lower educational levels and weaker labour market outcomes as well as a higher likelihood of receiving social income transfers, particularly among men. Assuming that the link is causal, our results indicate that individuals with schizophrenia or schizophrenia-related traits have a weakened ability to fully participate in the labour market, potentially reinforcing social exclusion.
Ladattava julkaisu This is an electronic reprint of the original article. |  |
