A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Weight gain in infancy and markers of cardiometabolic health in young adulthood
Tekijät: Nummela Saga R, Salo Pia, Pahkala Katja, Raitakari Olli T, Viikari Jorma, Rönnemaa Tapani, Jula Antti, Rovio Suvi P, Niinikoski Harri
Kustantaja: WILEY
Julkaisuvuosi: 2022
Journal: Acta Paediatrica
Tietokannassa oleva lehden nimi: ACTA PAEDIATRICA
Lehden akronyymi: ACTA PAEDIATR
Vuosikerta: 11
Numero: 8
Aloitussivu: 1603
Lopetussivu: 1611
Sivujen määrä: 9
ISSN: 0803-5253
DOI: https://doi.org/10.1111/apa.16349
Verkko-osoite: https://doi.org/10.1111/apa.16349
Rinnakkaistallenteen osoite: https://research.utu.fi/converis/portal/detail/Publication/175199881
Aim We studied whether repeatedly measured weight gain from birth up to age 2 years associated with cardiometabolic health in young adulthood. Methods Using the data collected in the longitudinal Special Turku Coronary Risk Factor Intervention Project, we investigated in 454 healthy subjects how early weight gain in six age intervals (birth to 7 months, 7-13 months, 13-18 months, 18-24 months, and birth to 13 and 24 months) associated with measures of cardiometabolic health at age 20 years. Linear regression analyses were controlled for (1) child's sex, intervention/control group, gestational age, baseline weight and change in length for each interval, and (2) parents' education, mother's weight before pregnancy, height and weight gain during pregnancy, and father's body mass index at the 7-month visit. Results Weight gain after the first year of life associated directly, when adjusted for traits of the child and parents, with systolic blood pressure, waist circumference and body mass index at age 20 years. In the fully adjusted analyses, weight gain from birth to 1 year and to 2 years of age associated inversely with insulin and insulin resistance. We found no association between early growth and diastolic blood pressure or serum lipids. Conclusion Early weight gain during first 2 years of life may predict later markers of cardiometabolic health.
Ladattava julkaisu This is an electronic reprint of the original article. |  |
