Gold Nanorods, DNA Origami, and Porous Silicon Nanoparticle-functionalized Biocompatible Double Emulsion for Versatile Targeted Therapeutics and Antibody Combination Therapy
: Feng Kong, Hongbo Zhang, Xiangmeng Qu, Xu Zhang, Dong Chen, Ruihua Ding, Ermei Mäkilä, Jarno Salonen, Hélder A. Santos, Mingtan Hai
Publisher: Wiley - V C H Verlag GmbH & Co. KGaA
: 2016
: Advanced Materials
: Advanced materials (Deerfield Beach, Fla.)
: Adv Mater
: 28
: 46
: 10195
: 10203
: 9
: 1521-4095
: 1521-4095
DOI: https://doi.org/10.1002/adma.201602763
: http://doi.wiley.com/10.1002/adma.201602763
Gold nanorods, DNA origami, and porous silicon nanoparticle-functionalized biocompatible double emulsion are developed for versatile molecular targeted therapeutics and antibody combination therapy. This advanced photothermal responsive all-in-one biocompatible platform can be easily formed with great therapeutics loading capacity for different cancer treatments with synergism and multidrug resistance inhibition, which has great potential in advancing biomedical applications.