A1 Refereed original research article in a scientific journal
Gold Nanorods, DNA Origami, and Porous Silicon Nanoparticle-functionalized Biocompatible Double Emulsion for Versatile Targeted Therapeutics and Antibody Combination Therapy
Authors: Feng Kong, Hongbo Zhang, Xiangmeng Qu, Xu Zhang, Dong Chen, Ruihua Ding, Ermei Mäkilä, Jarno Salonen, Hélder A. Santos, Mingtan Hai
Publisher: Wiley - V C H Verlag GmbH & Co. KGaA
Publication year: 2016
Journal: Advanced Materials
Journal name in source: Advanced materials (Deerfield Beach, Fla.)
Journal acronym: Adv Mater
Volume: 28
Issue: 46
First page : 10195
Last page: 10203
Number of pages: 9
ISSN: 1521-4095
eISSN: 1521-4095
DOI: https://doi.org/10.1002/adma.201602763
Web address : http://doi.wiley.com/10.1002/adma.201602763
Gold nanorods, DNA origami, and porous silicon nanoparticle-functionalized biocompatible double emulsion are developed for versatile molecular targeted therapeutics and antibody combination therapy. This advanced photothermal responsive all-in-one biocompatible platform can be easily formed with great therapeutics loading capacity for different cancer treatments with synergism and multidrug resistance inhibition, which has great potential in advancing biomedical applications.