Changes in total and unbound concentrations of sufentanil during target controlled infusion for cardiac surgery with cardiopulmonary bypass



: Jeleazcov C, Saari TI, Ihmsen H, Schuttler J, Fechner J

Publisher: OXFORD UNIV PRESS

: 2012

: British Journal of Anaesthesia

: BRITISH JOURNAL OF ANAESTHESIA

: BRIT J ANAESTH

: 109

: 5

: 698

: 706

: 9

: 0007-0912

DOI: https://doi.org/10.1093/bja/aes253


Neither total nor unbound sufentanil concentrations remained constant when performing a TCI with the Gepts model in coronary artery bypass surgery with CPB. A pharmacokinetic model derived from patients undergoing cardiac surgery with CPB might improve the performance of TCI in this population.



Last updated on 2024-26-11 at 14:00