A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Changes in total and unbound concentrations of sufentanil during target controlled infusion for cardiac surgery with cardiopulmonary bypass
Tekijät: Jeleazcov C, Saari TI, Ihmsen H, Schuttler J, Fechner J
Kustantaja: OXFORD UNIV PRESS
Julkaisuvuosi: 2012
Journal: British Journal of Anaesthesia
Tietokannassa oleva lehden nimi: BRITISH JOURNAL OF ANAESTHESIA
Lehden akronyymi: BRIT J ANAESTH
Vuosikerta: 109
Numero: 5
Aloitussivu: 698
Lopetussivu: 706
Sivujen määrä: 9
ISSN: 0007-0912
DOI: https://doi.org/10.1093/bja/aes253
Tiivistelmä
Neither total nor unbound sufentanil concentrations remained constant when performing a TCI with the Gepts model in coronary artery bypass surgery with CPB. A pharmacokinetic model derived from patients undergoing cardiac surgery with CPB might improve the performance of TCI in this population.
Neither total nor unbound sufentanil concentrations remained constant when performing a TCI with the Gepts model in coronary artery bypass surgery with CPB. A pharmacokinetic model derived from patients undergoing cardiac surgery with CPB might improve the performance of TCI in this population.