PhD Aapo Knuutila - UTU Research Portal

Aapo Knuutila
PhD

- Docent,
Department of Life Technologies (Faculty of Technology)

aajukn@utu.fi

+358 29 450 4582

+358 44 533 1025

Kiinamyllynkatu 10

Turku

: https://orcid.org/0000-0003-0622-5043

Bioteknologia; Diagnostiikka; Hinkuyskä; Rokotteet; Mikrobiologia

The effect of pertussis vaccination during pregnancy on the binding epitopes and avidity of anti-pertussis toxin IgG antibodies in infants and their mothers (2026)
- Journal of Infectious Diseases
Knuutila, Aapo; Ivaska, Lauri; Barkoff, Alex-Mikael; van Gageldonk, Pieter; Buisman, Annemarie; Mertsola, Jussi; He, Qiushui
Association of baseline cytokines with antibody concentrations after diphtheria-tetanus-acellular pertussis booster vaccination in Finnish children (2025)
- Vaccine
Anabe, Denise; Teräsjärvi, Johanna T.; Barkoff, Alex-Mikael; Knuutila, Aapo; Pape, Bernd; van Gageldonk, Pieter; Buisman, Annemarie; Mertsola, Jussi; He, Qiushui
Prior immunological memory to pertussis toxin affects the avidity development of anti-PT IgG antibodies after acellular pertussis booster vaccination (2025)
- Emerging microbes & infections
Knuutila, Aapo; Ahvenainen, Niina; Barkoff, Alex-Mikael; Mertsola, Jussi; van Gageldonk, Pieter; Buisman, Annemarie; Valente Pinto, Marta; Kelly, Dominic; He, Qiushui
A novel whole blood assay to quantify the release of T cell associated cytokines in response to Bordetella pertussis antigens (2024)
- Journal of Immunological Methods
Pinto, Marta Valente; Barkoff, Alex-Mikael; Bibi, Sagida; Knuutila, Aapo; Teräsjärvi, Johanna; Clutterbuck, Elizabeth; Gimenez-Fourage, Sophie; Pagnon, Anke; van Gaans-van den Brink, Jacqueline A.M.; Corbiere, Veronique; De Montfort, Aymeric; Saso, Anja; Jobe, Haddijatou; Roetynck, Sophie; Kampmann, Beate; Simonetti, Elles; Diavatopoulos, Dimitri; Lambert, Eleonora E.; Mertsola, Jussi; Blanc, Pascal; van Els, Cécile A. C. M.; Dominic Kelly, Dominic; He, Qiushui; The PERISCOPE Consortium
Characteristics of anti-pertussis toxin antibodies after vaccination and infection (2024) Knuutila, Aapo
Antibody avidity to pertussis toxin after acellular pertussis vaccination and infection (2023)
- Emerging microbes & infections
Knuutila Aapo, Dalby Tine, Ahvenainen Niina, Barkoff Alex-Mikael, Jørgensen Charlotte Sværke, Fuursted Kurt, Mertsola Jussi, He Qiushui
Effect of immunization during pregnancy and pre-existing immunity on diphtheria-tetanus-acellular pertussis vaccine responses in infants (2023)
- Emerging microbes & infections
Knuutila Aapo, Barkoff Alex Mikael, Ivaska Lauri, Tenhu Elina, Teräsjärvi Johanna, van Gageldonk Pieter, Buisman Annemarie, Mertsola Jussi, He Qiushui; and PERISCOPE consortium
Oral fluid-based lateral flow point-of-care assays for pertussis serology (2023)
- Journal of Medical Microbiology
Knuutila Aapo, Duncan John, Li Fu, Eletu Seyi, Litt David, Fry Norman, He Qiushui
Vaccine Antigen Deficiency Does Not Substantially Affect the Identification of Bordetella pertussis Strains by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (2023)
- Journal of Clinical Microbiology
Knuutila Aapo, Harju Inka, Korhonen Suvi, Mäkelä Joonatan, Backström Lucas, Barkoff Alex-Mikael, He Qiushui
Memory B Cell Activation Induced by Pertussis Booster Vaccination in Four Age Groups of Three Countries (2022)
- Frontiers in immunology
Versteegen Pauline, Barkoff Alex-Mikael, Valente Pinto Marta, Van De Kasteele Jan, Knuutila Aapo, Bibi Sagida, De Rond Lia, Teräsjärvi Johanna, Sanders Katherine, De Zeeuw-Brouwer Mary-lene, Luoto Raakel, Ten Hulscher Hinke, Clutterbuck Elizabeth A., Sanders Elisabeth A. M., Mertsola Jussi, Berbers Guy A. M., He Qiushui, Kelly Dominic F., Buisman Anne-Marie; PERISCOPE Consortium
Pertussis toxin neutralizing antibody response after an acellular booster vaccination in Dutch and Finnish participants of different age groups (2022)
- Emerging microbes & infections
Knuutila Aapo, Versteegen Pauline, Barkoff Alex-Mikael, van Gageldonk Pieter, Mertsola Jussi, Berbers Guy, He Qiushui; PERISCOPE Consortium
Whole blood based point-of-care assay for the detection of anti-pertussis toxin IgG antibodies (2022)
- Journal of Immunological Methods
Knuutila Aapo, Rautanen Carita, Barkoff Alex-Mikael, Mertsola Jussi, He Qiushui
Evaluation of Anti-PT Antibody Response after Pertussis Vaccination and Infection: The Importance of Both Quantity and Quality (2021)
- Toxins
Barkoff Alex-Mikael, Knuutila Aapo, Mertsola Jussi, He Qiushui
Simultaneous Determination of Antibodies to Pertussis Toxin and Adenylate Cyclase Toxin Improves Serological Diagnosis of Pertussis (2021)
- Diagnostics
Knuutila Aapo, Barkoff Alex M, Mertsola Jussi, Osicka Radim, Sebo Peter, He Qiushui
Widespread circulation of pertussis in Finland during 1968-1972 when the whole cell vaccine was in use (2021)
- Clinical Microbiology and Infection
Ahvenainen Niina, Dub Timothee, Knuutila Aapo, Barkoff Alex M, Sane Jussi, He Quishui
Differences in epitope-specific antibodies to pertussis toxin after infection and acellular vaccinations (2020)
- Clinical and Translational Immunology
Aapo Knuutila, Tine Dalby, Alex-Mikael Barkoff, Charlotte Sværke Jørgensen, Kurt Fuursted, Jussi Mertsola, Kevin Markey, Qiushui He
Multiplex Point-of-Care Tests for the Determination of Antibodies after Acellular Pertussis Vaccination (2020)
- Diagnostics
Aapo Knuutila, Carita Rautanen, Jussi Mertsola, Qiushui He
A rapid lateral flow immunoassay for serological diagnosis of pertussis (2018)
- Vaccine
Salminen T, Knuutila A, Barkoff AM, Mertsola J, He QS
Low-Cost Chemical Sensing Platform With Organic Polymer Functionalization (2015)
- IEEE Electron Device Letters
Kaisti M, Knuutila A, Boeva Z, Kvarnstrom C, Levon K