PhD Aapo Knuutila - UTU Tutkimustietojärjestelmä

Aapo Knuutila
PhD

- University Teacher,
Biotechnology (Department of Life Technologies)

aajukn@utu.fi

+358 29 450 4582

+358 44 533 1025

Kiinamyllynkatu 10

Turku

ORCID identifier: https://orcid.org/0000-0003-0622-5043

Areas of expertise

Bioteknologia; Diagnostiikka; Hinkuyskä; Rokotteet; Mikrobiologia

Research

Teaching

Kurssit:

Johdatus biotekniikkaan, In vitro -diagnostiikan harjoitukset, Biotekniikan järjestelmät ja analyysialustat

Kehitän:

Virtuaalitodellisuuteen perustuvia laboratoriokoulutusmenetelmiä

Publications

Association of baseline cytokines with antibody concentrations after diphtheria-tetanus-acellular pertussis booster vaccination in Finnish children (2025)
- Vaccine
Anabe, Denise; Teräsjärvi, Johanna T.; Barkoff, Alex-Mikael; Knuutila, Aapo; Pape, Bernd; van Gageldonk, Pieter; Buisman, Annemarie; Mertsola, Jussi; He, Qiushui
(A1 Refereed original research article in a scientific journal)
Prior immunological memory to pertussis toxin affects the avidity development of anti-PT IgG antibodies after acellular pertussis booster vaccination (2025)
- Emerging microbes & infections
Knuutila, Aapo; Ahvenainen, Niina; Barkoff, Alex-Mikael; Mertsola, Jussi; van Gageldonk, Pieter; Buisman, Annemarie; Valente Pinto, Marta; Kelly, Dominic; He, Qiushui
(A1 Refereed original research article in a scientific journal)
A novel whole blood assay to quantify the release of T cell associated cytokines in response to Bordetella pertussis antigens (2024)
- Journal of Immunological Methods
Pinto, Marta Valente; Barkoff, Alex-Mikael; Bibi, Sagida; Knuutila, Aapo; Teräsjärvi, Johanna; Clutterbuck, Elizabeth; Gimenez-Fourage, Sophie; Pagnon, Anke; van Gaans-van den Brink, Jacqueline A.M.; Corbiere, Veronique; De Montfort, Aymeric; Saso, Anja; Jobe, Haddijatou; Roetynck, Sophie; Kampmann, Beate; Simonetti, Elles; Diavatopoulos, Dimitri; Lambert, Eleonora E.; Mertsola, Jussi; Blanc, Pascal; van Els, Cécile A. C. M.; Dominic Kelly, Dominic; He, Qiushui; The PERISCOPE Consortium
(A1 Refereed original research article in a scientific journal)
Characteristics of anti-pertussis toxin antibodies after vaccination and infection (2024) Knuutila Aapo
(G5 Article dissertation )
Antibody avidity to pertussis toxin after acellular pertussis vaccination and infection (2023)
- Emerging microbes & infections
Knuutila Aapo, Dalby Tine, Ahvenainen Niina, Barkoff Alex-Mikael, Jørgensen Charlotte Sværke, Fuursted Kurt, Mertsola Jussi, He Qiushui
(A1 Refereed original research article in a scientific journal)
Effect of immunization during pregnancy and pre-existing immunity on diphtheria-tetanus-acellular pertussis vaccine responses in infants (2023)
- Emerging microbes & infections
Knuutila Aapo, Barkoff Alex Mikael, Ivaska Lauri, Tenhu Elina, Teräsjärvi Johanna, van Gageldonk Pieter, Buisman Annemarie, Mertsola Jussi, He Qiushui; and PERISCOPE consortium
(A1 Refereed original research article in a scientific journal)
Oral fluid-based lateral flow point-of-care assays for pertussis serology (2023)
- Journal of Medical Microbiology
Knuutila Aapo, Duncan John, Li Fu, Eletu Seyi, Litt David, Fry Norman, He Qiushui
(A1 Refereed original research article in a scientific journal)
Vaccine Antigen Deficiency Does Not Substantially Affect the Identification of Bordetella pertussis Strains by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (2023)
- Journal of Clinical Microbiology
Knuutila Aapo, Harju Inka, Korhonen Suvi, Mäkelä Joonatan, Backström Lucas, Barkoff Alex-Mikael, He Qiushui
(B1 Non-refereed article in a scientific journal)
Memory B Cell Activation Induced by Pertussis Booster Vaccination in Four Age Groups of Three Countries (2022)
- Frontiers in immunology
Versteegen Pauline, Barkoff Alex-Mikael, Valente Pinto Marta, Van De Kasteele Jan, Knuutila Aapo, Bibi Sagida, De Rond Lia, Teräsjärvi Johanna, Sanders Katherine, De Zeeuw-Brouwer Mary-lene, Luoto Raakel, Ten Hulscher Hinke, Clutterbuck Elizabeth A., Sanders Elisabeth A. M., Mertsola Jussi, Berbers Guy A. M., He Qiushui, Kelly Dominic F., Buisman Anne-Marie; PERISCOPE Consortium
(A1 Refereed original research article in a scientific journal)
Pertussis toxin neutralizing antibody response after an acellular booster vaccination in Dutch and Finnish participants of different age groups (2022)
- Emerging microbes & infections
Knuutila Aapo, Versteegen Pauline, Barkoff Alex-Mikael, van Gageldonk Pieter, Mertsola Jussi, Berbers Guy, He Qiushui; PERISCOPE Consortium
(A1 Refereed original research article in a scientific journal)
Whole blood based point-of-care assay for the detection of anti-pertussis toxin IgG antibodies (2022)
- Journal of Immunological Methods
Knuutila Aapo, Rautanen Carita, Barkoff Alex-Mikael, Mertsola Jussi, He Qiushui
(A1 Refereed original research article in a scientific journal)
Evaluation of Anti-PT Antibody Response after Pertussis Vaccination and Infection: The Importance of Both Quantity and Quality (2021)
- Toxins
Barkoff Alex-Mikael, Knuutila Aapo, Mertsola Jussi, He Qiushui
(A2 Refereed review article in a scientific journal )
Simultaneous Determination of Antibodies to Pertussis Toxin and Adenylate Cyclase Toxin Improves Serological Diagnosis of Pertussis (2021)
- Diagnostics
Knuutila Aapo, Barkoff Alex M, Mertsola Jussi, Osicka Radim, Sebo Peter, He Qiushui
(A1 Refereed original research article in a scientific journal)
Widespread circulation of pertussis in Finland during 1968-1972 when the whole cell vaccine was in use (2021)
- Clinical Microbiology and Infection
Ahvenainen Niina, Dub Timothee, Knuutila Aapo, Barkoff Alex M, Sane Jussi, He Quishui
(B1 Non-refereed article in a scientific journal)
Differences in epitope-specific antibodies to pertussis toxin after infection and acellular vaccinations (2020)
- Clinical and Translational Immunology
Aapo Knuutila, Tine Dalby, Alex-Mikael Barkoff, Charlotte Sværke Jørgensen, Kurt Fuursted, Jussi Mertsola, Kevin Markey, Qiushui He
(A1 Refereed original research article in a scientific journal)
Multiplex Point-of-Care Tests for the Determination of Antibodies after Acellular Pertussis Vaccination (2020)
- Diagnostics
Aapo Knuutila, Carita Rautanen, Jussi Mertsola, Qiushui He
(A1 Refereed original research article in a scientific journal)
A rapid lateral flow immunoassay for serological diagnosis of pertussis (2018)
- Vaccine
Salminen T, Knuutila A, Barkoff AM, Mertsola J, He QS
(A1 Refereed original research article in a scientific journal)
Low-Cost Chemical Sensing Platform With Organic Polymer Functionalization (2015)
- IEEE Electron Device Letters
Kaisti M, Knuutila A, Boeva Z, Kvarnstrom C, Levon K
(A1 Refereed original research article in a scientific journal)