Jussi Lehto - UTU Research Portal

Jussi Lehto

InFLAMES Flagship (Faculty of Medicine)

juleht@utu.fi

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Association between post-COVID-19 neuropsychiatric symptoms and persistent glial activation in the limbic system: a TSPO PET study (2026)
- Journal of Neurology
Tuomaala, Joel; Saraste, Maija; Smith, Emma; Kuusi, Matilda; Westerberg, Elisabet; Honkonen, Eveliina; Kargar, Rahim; Laaksonen, Sini; Lehto, Jussi; Luoma, Amelie; Matilainen, Markus; Misin, Olavi; Atosuo, Janne; Kanerva, Mari; Liira, Helena; Laakso, Sini; Posharina, Tatiana; Saunavaara, Virva; Wahlroos, Saara; Rajander, Johan; Airas, Laura
Broad rim lesions are a new pathological and imaging biomarker for rapid disease progression in multiple sclerosis (2025)
- Nature Medicine
Klotz, Luisa; Smolders, Joost; Lehto, Jussi; Matilainen, Markus; Lütje, Lukas; Buchholz, Luzia; Albrecht, Stefanie; Walter, Carolin; Varghese, Julian; Wiendl, Heinz; Nylund, Marjo; Thomas, Christian; Gardberg, Maria; van den Bosch, Aletta M. R.; Airas, Laura; Huitinga, Inge; Kuhlmann, Tanja
Longitudinal accumulation of glial activation measured by TSPO-PET predicts later brain atrophy in multiple sclerosis (2025)
- Journal of Neuroinflammation
Nylund, Marjo; Lehto, Jussi; Matilainen, Markus; Rajander, Johan; Wahlroos, Saara; Sucksdorff, Marcus; Kuhlmann, Tanja; Airas, Laura
Plasma CHI3L1 associates with brain volume loss and glial activation in multiple sclerosis (2025)
- Journal of Neurology, Neurosurgery and Psychiatry
Ahola, Venla; Saraste, Maija; Nylund, Marjo; Matilainen, Markus; Luoma, Amelie; Vuorimaa, Anna; Lehto, Jussi; Laaksonen, Sini; Brockmann, Eeva-Christine; Kuhle, Jens; Leppert, David; Soukka, Tero; Lamminmäki, Urpo; Airas, Laura
Synaptic Density in Multiple Sclerosis (2025)
- Neurology, Neuroimmunology and Neuroinflammation
Luoma, Amelie; Matilainen, Markus; Tuisku, Jouni Mikael; Aarnio, Richard; Nikkilä, Taru; Laaksonen, Sini; Koivumäki, Mikko; Honkonen, Eveliina; Nylund, Marjo; Wahlroos, Saara; Solin, Olof; Chen, Ming-Kai; Toyonaga, Takuya; Lehto, Jussi; Snellman, Anniina; Rinne, Juha O.; Airas, Laura M.
P2X 7-receptor binding in new-onset and secondary progressive MS – a [11C]SMW139 PET study (2024)
- EJNMMI Research
Lehto, Jussi; Aarnio, Richard; Tuisku, Jouni; Sucksdorff, Marcus; Koivumäki, Esa Mikko; Nylund, Marjo; Helin, Semi; Rajander, Johan; Danon, Jonathan; Gilchrist, Jayson; Kassiou, Michael; Oikonen, Vesa; Airas, Laura
Synaptic density in multiple sclerosis: An in vivo study using [11C]UCB-J-PET imaging (2024)
- Multiple Sclerosis
Luoma, Amelie; Matilainen, Markus; Tuisku, Jouni; Aarnio, Richard; Nikkila, Taru; Laaksonen, Sini; Koivumaki, Mikko; Honkonen, Eveliina; Nylund, Marjo; Wahlroos, Saara; Toyonaga, Takuya; Chen, Ming-Kai; Lehto, Jussi; Snellman, Anniina; Rinne, Juha; Airas, Laura
TSPO-PET-measurable microglial activity remains unaltered in cladribine-treated RRMS patients (2024)
- Multiple Sclerosis
Rajalehto, Olli; Saraste, Maija; Matilainen, Markus; Nylund, Marjo; Honkonen, Eveliina; Lehto, Jussi; Airas, Laura
Longitudinal stability of progression-related microglial activity during teriflunomide treatment in patients with multiple sclerosis (2023)
- European Journal of Neurology
Lehto Jussi, Nylund Marjo, Matilainen Markus, Sucksdorff Marcus, Vuorimaa Anna, Rajander Johan, Wahlroos Saara, Hariri Parisa, Laura Airas
PET-measurable innate immune cell activation reduction in chronic active lesions in PPMS brain after rituximab treatment: a case report (2023)
- Journal of Neurology
Lehto Jussi, Sucksdorff Marcus, Nylund Marjo, Raitanen Roope, Matilainen Markus, Airas Laura