Jussi Lehto - UTU Research Portal

Jussi Lehto

InFLAMES Flagship (Faculty of Medicine)

juleht@utu.fi

Publications

P2X 7-receptor binding in new-onset and secondary progressive MS – a [11C]SMW139 PET study (2024)
- EJNMMI Research
Lehto, Jussi; Aarnio, Richard; Tuisku, Jouni; Sucksdorff, Marcus; Koivumäki, Esa Mikko; Nylund, Marjo; Helin, Semi; Rajander, Johan; Danon, Jonathan; Gilchrist, Jayson; Kassiou, Michael; Oikonen, Vesa; Airas, Laura
(A1 Refereed original research article in a scientific journal)
Synaptic density in multiple sclerosis: An in vivo study using [11C]UCB-J-PET imaging (2024)
- Multiple Sclerosis
Luoma, Amelie; Matilainen, Markus; Tuisku, Jouni; Aarnio, Richard; Nikkila, Taru; Laaksonen, Sini; Koivumaki, Mikko; Honkonen, Eveliina; Nylund, Marjo; Wahlroos, Saara; Toyonaga, Takuya; Chen, Ming-Kai; Lehto, Jussi; Snellman, Anniina; Rinne, Juha; Airas, Laura
(Abstract)
TSPO-PET-measurable microglial activity remains unaltered in cladribine-treated RRMS patients (2024)
- Multiple Sclerosis
Rajalehto, Olli; Saraste, Maija; Matilainen, Markus; Nylund, Marjo; Honkonen, Eveliina; Lehto, Jussi; Airas, Laura
(Poster)
Longitudinal stability of progression-related microglial activity during teriflunomide treatment in patients with multiple sclerosis (2023)
- European Journal of Neurology
Lehto Jussi, Nylund Marjo, Matilainen Markus, Sucksdorff Marcus, Vuorimaa Anna, Rajander Johan, Wahlroos Saara, Hariri Parisa, Laura Airas
(A1 Refereed original research article in a scientific journal)
PET-measurable innate immune cell activation reduction in chronic active lesions in PPMS brain after rituximab treatment: a case report (2023)
- Journal of Neurology
Lehto Jussi, Sucksdorff Marcus, Nylund Marjo, Raitanen Roope, Matilainen Markus, Airas Laura
(B1 Non-refereed article in a scientific journal)
The effect of an apple polyphenol extract rich in epicatechin and flavan-3-ol oligomers on brachial artery flow-mediated vasodilatory function in volunteers with elevated blood pressure (2017)
- Nutrition Journal
Saarenhovi M, Salo P, Scheinin M, Lehto J, Lovro Z, Tiihonen K, Lehtinen MJ, Junnila J, Hasselwander O, Tarpila A, Raitakari OT
(A1 Refereed original research article in a scientific journal)
Detecting a dexmedetomidine-evoked reduction of noradrenaline release in the human brain with the α2C-adrenoceptor PET ligand [11C]ORM-13070 (2016)
- Synapse
Lehto J, Scheinin A, Johansson J, Marjamäki P, Arponen E, Scheinin H, Scheinin M
(A1 Refereed original research article in a scientific journal)
Application of cross-species PET imaging to assess neurotransmitter release in brain (2015)
- Psychopharmacology
Finnema SJ, Scheinin M, Shahid M, Lehto J, Borroni E, Bang-Andersen B, Sallinen J, Wong E, Farde L, Halldin C, Grimwood S
(A2 Refereed review article in a scientific journal )
Imaging of a2C-adrenoceptors in the living brain: a method to monitor noradrenaline release? (2015)
- SpringerPlus
Scheinin M, Lehto J, Johansson J, Luoto P, Arponen E, Vuorilehto L, Scheinin H, Rouru J
(Other publication)
Sensitivity of [C-11]ORM-13070 to increased extracellular noradrenaline in the CNS - a PET study in human subjects (2015)
- Psychopharmacology
Lehto J, Johansson J, Vuorilehto L, Luoto P, Arponen E, Scheinin H, Rouru J, Scheinin M
(A1 Refereed original research article in a scientific journal)
Test-retest reliability of (11)C-ORM-13070 in PET imaging of α2C-adrenoceptors in vivo in the human brain (2015)
- European Journal of Nuclear Medicine and Molecular Imaging
Jussi Lehto, Jere R. Virta, Vesa Oikonen, Anne Roivainen, Pauliina Luoto, Eveliina Arponen, Semi Helin, Johanna Hietamäki, Aila Holopainen, Marita Kailajärvi, Juha M. Peltonen, Juha Rouru, Jukka Sallinen, Kirsi Virtanen, Iina Volanen, Mika Scheinin, Juha O. Rinne
(A1 Refereed original research article in a scientific journal)
The alpha2C-adrenoceptor as a neuropsychiatric drug tar-get - PET studies in human subjects (2015) Lehto Jussi
(G5 Article dissertation )
Validation of [11C]ORM-13070 as a PET tracer for alpha2c-adrenoceptors in the human brain (2015)
- Synapse
Jussi Lehto, Mika M. Hirvonen, Jarkko Johansson, Jukka Kemppainen, Pauliina Luoto, Tarja Naukkarinen, Vesa Oikonen, Eveliina Arponen, Juha Rouru, Jukka Sallinen, Harry Scheinin, Lauri Vuorilehto, Sjoerd J. Finnema, Christer Halldin, Juha O. Rinne, Mika Scheinin
(A1 Refereed original research article in a scientific journal)