Eero Rissanen
MD, PhD, neurology consultant
eerris@utu.fi Työhuone: 6006 ORCID-tunniste: https://orcid.org/https://orcid.org/0000-0001-5677-8856 |
Neurology; neuroimmunology; multiple sclerosis; neuroinflammation; PET; MRI
I am clinical neurologist and a clinical researher in Turku Univerity Hospital (Tyks) and University of Turku. As my main clinical duty in the Division of Clinical Neurosciences in Tyks, I have worked as the chief physician in the neurology outpatient polyclinic in Tyks Vakka-Suomi Hospital in Uusikaupunki since 2013. I attained my MD degree in 2005 and neurology consultant degree in 2011, both in the University of Turku.
Alongside my clinical duties, I have worked as a part time clinical researcher in professor Laura Airas's research group in Turku PET Centre and Division of Clinical Neurosciences in Tyks since 2009. I defended my doctoral thesis, entitled "Imaging neuroinflammation in progressive multiple sclerosis" in Turku University in 2015. Thereafter, I have continued as a part time postdoctoral researher in professor Airas's group.
The main topic of my research has been the imaging of neuroinflammation in progressive multiple sclerosis, with the focus on activated microglia and adenosine A2A receptors. The fore mentioned targets can be visualized by the means of specific radioligands and positron emission tomography (PET). Recently, we have also been developing imaging and other biomarker methods for the evaluation of activated astrocytes. Neuroinflammation with astroglial activation (i.e. activation of microglia and astrocytes) is one of the hallmarks of disease pathology in many neuroinflammatory and neurodegenerative disorders. Thus, evaluating astroglial activation in vivo by the means of PET and advanced MR imaging will provide further understanding in the mechanisms and temporal evolution of these disease processes, and may provide new targets for developing disease modifying treatments in the future.
The work in our reseach group is highly multidisciplinary including collaboration with radiochemists, radiographers, mathematicians, physicists and clinical doctors as well as basic researchers with various backgrounds from biosciences.
In clinical neurology as well as in clinical research, teaching is one of the core responsibilities, and at the same time a great privilege, for the senior doctors. I have participated in teaching of clinical neurology as a clinical teacher for the medical students in the neurology courses in Turku University in 2015, 2016, 2018 and 2019. I have also given several lectures in other university courses, such as in the Neurology for Neuroscientists course carried out by the Turku Brain and Mind Center. In addition, I have participated in numerous educational events as an invited speaker, the themes being mainly on clinical neuroimmunology and imaging of neuroinflammation.
In our research group, I am supervising master's and doctoral students alongside our primary investigator, professor Laura Airas.
I have also attained the subspecialty of Medical Education (The Finnish Medical Association) in 2018.
- Adenosine A2A receptor availability in cerebral gray and white matter of patients with Parkinson's disease (2023)
- Parkinsonism and Related Disorders
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Adenosine A2A receptor availability in patients with early- and moderate-stage Parkinson’s disease (2023)
- Journal of Neurology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Circulating neurofilament is linked with morbid obesity, renal function, and brain density (2022)
- Scientific Reports
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Differences in brain changes between adults with childhood-onset epilepsy and controls: A prospective population-based study (2022)
- Acta Neurologica Scandinavica
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Innate Immune Cell-Related Pathology in the Thalamus Signals a Risk for Disability Progression in Multiple Sclerosis (2022)
- Neurology, Neuroimmunology and Neuroinflammation
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Effect of dopaminergic medication on adenosine 2A receptor availability in patients with Parkinson's disease (2021)
- Parkinsonism and Related Disorders
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Fingolimod treatment reverses signs of diffuse white matter damage in multiple sclerosis: A pilot study (2021)
- Multiple Sclerosis and Related Disorders
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - High serum neurofilament associates with diffuse white matter damage in MS (2021)
- Neurology, Neuroimmunology and Neuroinflammation
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Whole Brain Adiabatic T-1rho and Relaxation Along a Fictitious Field Imaging in Healthy Volunteers and Patients With Multiple Sclerosis: Initial Findings (2021)
- Journal of Magnetic Resonance Imaging
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Brain TSPO-PET predicts later disease progression independent of relapses in multiple sclerosis (2020)
- Brain
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Decreased Availability of Adenosine 2A Receptors in the Caudate in Patients with Early Stage Parkinson’s Disease (2020)
- Movement Disorders
(O2 Muu julkaisu ) - Effect of Dopaminergic Medication on Adenosine 2A Receptor Availability in Patients with Parkinson’s Disease (2020) Imran Waggan, Jouni Tuisku, Markus Matilainen, Semi Helin, Riitta Parkkola, Eero Rissanen, Juha Rinne, Laura Airas,
(O2 Muu julkaisu ) - Insights into disseminated MS brain pathology with multimodal diffusion tensor and PET imaging (2020)
- Neurology, Neuroimmunology and Neuroinflammation
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Rituximab in the treatment of multiple sclerosis in the Hospital District of Southwest Finland (2020)
- Multiple Sclerosis and Related Disorders
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Serum glial fibrillary acidic protein correlates with multiple sclerosis disease severity (2020)
- Multiple Sclerosis
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Effects of age, BMI and sex on the glial cell marker TSPO - a multicentre [C-11]PBR28 HRRT PET study (2019)
- European Journal of Nuclear Medicine and Molecular Imaging
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Natalizumab treatment reduces microglial activation in the white matter of the MS brain (2019)
- Neurology, Neuroimmunology and Neuroinflammation
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Progressive dopaminergic defect in a patient with primary progressive multiple sclerosis (2019)
- Multiple Sclerosis and Related Disorders
(B1 Vertaisarvioimaton kirjoitus tieteellisessä lehdessä ) - Rituksimabi MS-taudin hoidossa (2019)
- Duodecim
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Brain amyloid load and its associations with cognition and vascular risk factors in FINGER study (2018)
- Neurology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )