Adjunct professor, MD, Gynecologic oncologist Johanna Hynninen - UTU Research Portal

Johanna Hynninen
Adjunct professor, MD, Gynecologic oncologist

- Docent,
Department of Clinical Medicine (Faculty of Medicine)
- ,
Obstetrics and Gynaecology (Department of Clinical Medicine)

mijohy@utu.fi

: https://orcid.org/0000-0002-0854-7225

gynaecologic oncology; ovarian cancer

https://sites.utu.fi/ovariancancer/ https://www.deciderproject.eu

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Association of clinical and laboratory variables with risk of venous thromboembolism in high-grade serous ovarian cancer (2025)
- International Journal of Gynecological Cancer
Peippo, Maija H.; Perkonoja, Katariina; Isoviita, Veli-Matti; Hynninen, Johanna; Lassila, Riitta; Carpén, Olli
MUC1 and glycan probing of CA19-9 captured biomarkers from cyst fluids and serum provides enhanced recognition of ovarian cancer (2025)
- Scientific Reports
Afrin Ruma, Shamima; Vinod, Rufus; Jain, Shruti; Huhtinen, Kaisa; Hynninen, Johanna; Leivo, Janne; Pettersson, Kim; Sundfeldt, Karin; Gidwani, Kamlesh
Multi-omics analysis reveals the attenuation of the interferon pathway as a driver of chemo-refractory ovarian cancer (2025)
- Cell Reports Medicine
Afenteva, Daria; Yu, Rong; Rajavuori, Anna; Salvadores, Marina; Launonen, Inga-Maria; Lavikka, Kari; Zhang, Kaiyang; Pirttikoski, Anna; Marchi, Giovanni; Jamalzadeh, Sanaz; Isoviita, Veli-Matti; Li, Yilin; Micoli, Giulia; Erkan, Erdogan Pekcan; Falco, Matias M.; Ungureanu, Daniela; Lahtinen, Alexandra; Oikkonen, Jaana; Hietanen, Sakari; Vähärautio, Anna; Sur, Inderpreet; Virtanen, Anni; Färkkilä, Anniina; Hynninen, Johanna; Muranen, Taru A.; Taipale, Jussi; Hautaniemi, Sampsa
Novel glycovariant biomarkers of CA125 and CA15-3 and their diagnostic performance across histotypes of ovarian cancer: A multi-cohort study in Sweden and Finland (2025)
- European Journal of Obstetrics and Gynecology and Reproductive Biology
Roos Alexander, Hanna; Jain, Shruti; Gidwani, Kamlesh; Ulfenborg, Benjamin; Ottander, Ulrika; Lundin, Eva; Hynninen, Johanna; Afrin Ruma, Shamima; Huhtinen, Kaisa; Sundfeldt, Karin; Pettersson, Kim; Idahl, Annika
A synthetic lethal dependency on casein kinase 2 in response to replication-perturbing therapeutics in RB1-deficient cancer cells (2024)
- Science Advances
Bulanova, Daria; Akimov, Yevhen; Senkowski, Wojciech; Oikkonen, Jaana; Gall-Mas, Laura; Timonen, Sanna; Elmadani, Manar; Hynninen, Johanna; Hautaniemi, Sampsa; Aittokallio, Tero; Wennerberg, Krister
Bexmarilimab Activates Human Tumor-Associated Macrophages to Support Adaptive Immune Responses in Interferon-Poor Immune Microenvironments (2024)
- Cancer Immunology Research
Rannikko Jenna H., Bono Petri, Hynninen Johanna, Hollmén Maija
Chemotherapy induces myeloid-driven spatially confined T cell exhaustion in ovarian cancer (2024)
- Cancer Cell
Launonen, Inga-Maria; Niemiec, Iga; Hincapié-Otero, María; Erkan, Pekcan Erdogan; Junquera, Ada; Afenteva, Daria; Falco, Matias M.; Liang, Zhihan; Salko, Matilda; Chamchougia, Foteini; Szabo, Angela; Perez-Villatoro, Fernando; Li, Yilin; Micoli, Giulia; Nagaraj, Ashwini; Haltia, Ulla-Maija; Kahelin, Essi; Oikkonen, Jaana; Hynninen, Johanna; Virtanen, Anni; Nirmal, Ajit J.; Vallius, Tuulia; Hautaniemi, Sampsa; Sorger, Peter K.; Vähärautio, Anna; Färkkilä, Anniina
Deciphering cancer genomes with GenomeSpy : a grammar-based visualization toolkit (2024)
- GigaScience
Lavikka, Kari; Oikkonen, Jaana; Li, Yilin; Muranen, Taru; Micoli, Giulia; Marchi, Giovanni; Lahtinen, Alexandra; Huhtinen, Kaisa; Lehtonen, Rainer; Hietanen, Sakari; Hynninen, Johanna; Virtanen, Anni; Hautaniemi, Sampsa
Extensive mutational ctDNA profiles reflect High-grade serous cancer tumors and reveal emerging mutations at recurrence (2024)
- Translational Oncology
Marchi Giovanni, Rajavuori Anna, Nguyen Mai T. N., Huhtinen Kaisa, Oksa Sinikka, Hietanen Sakari, Hautaniemi Sampsa, Hynninen Johanna, Oikkonen Jaana
Genome-wide quantification of copy-number aberration impact on gene expression in ovarian high-grade serous carcinoma (2024)
- BMC Cancer
Jamalzadeh Sanaz, Dai Jun, Lavikka Kari, Li Yilin, Jiang Jing, Huhtinen Kaisa, Virtanen Anni, Oikkonen Jaana, Hietanen Sakari, Hynninen Johanna, Vähärautio Anna, Häkkinen Antti, Hautaniemi Sampsa
HRD related signature 3 predicts clinical outcome in advanced tubo-ovarian high-grade serous carcinoma (2024)
- Gynecologic Oncology
Koskela Heidi, Li Yilin, Joutsiniemi Titta, Muranen Taru, Isoviita Veli-Matti, Huhtinen Kaisa, Micoli Giulia, Lavikka Kari, Marchi Giovanni, Hietanen Sakari, Virtanen Anni, Hautaniemi Sampsa, Oikkonen Jaana, Hynninen Johanna
Is it safe to operate selected low-risk endometrial cancer patients in secondary hospitals? (2024)
- EJSO - European Journal of Surgical Oncology
Narva Sara, Polo-Kantola Päivi, Oksa Sinikka, Kallio Johanna, Huvila Jutta, Rissanen Tiia, Hynninen Johanna, Hietanen Sakari, Joutsiniemi Titta
Kohdunrungon syövän diagnostiikka (2024) Syöpäsairaudet Puistola, Ulla; Mäenpää, Johanna; Staff, Synnöve; Hynninen, Johanna
Kohdunrungon syövän hoito (2024) Syöpäsairaudet Puistola, Ulla; Mäenpää, Johanna; Lindholm, Paula; Staff, Synnöve; Hynninen, Johanna
Kohdunrungon syövän yleisyys, vaaratekijät ja esiasteet (2024) Syöpäsairaudet Puistola, Ulla; Mäenpää, Johanna; Staff, Synnöve; Hynninen, Johanna
Kohtusarkoomat (2024) Syöpäsairaudet Puistola, Ulla; Mäenpää, Johanna; Staff, Synnöve; Hynninen, Johanna
Locus-specific LINE-1 expression in clinical ovarian cancer specimens at the single-cell level (2024)
- Scientific Reports
Perkiö Anna, Pradhan Barun, Genc Fatih, Pirttikoski Anna, Pikkusaari Sanna, Erkan Erdogan Pekcan, Falco Matias Marin, Huhtinen Kaisa, Narva Sara, Hynninen Johanna, Kauppi Liisa, Vähärautio Anna
PIK3R1 fusion drives chemoresistance in ovarian cancer by activating ERK1/2 and inducing rod and ring-like structures (2024)
- Neoplasia
Rausio Heidi, Cervera Alejandra, Heuser Vanina D., West Gun, Oikkonen Jaana, Pianfetti Elena, Lovino Marta, Ficarra Elisa, Taimen Pekka, Hynninen Johanna, Lehtonen Rainer, Hautaniemi Sampsa, Carpén Olli, Huhtinen Kaisa
Trofoblastisairaudet (2024) Syöpäsairaudet Mäenpää, Johanna; Puistola, Ulla; Urpilainen, Elina; Hynninen, Johanna
Trofoblastisairaudet (2024) Syöpäsairaudet Mäenpää, Johanna; Puistola, Ulla; Urpilainen, Elina; Hynninen, Johanna