Adjunct professor, MD, Gynecologic oncologist Johanna Hynninen - UTU Research Portal

Johanna Hynninen
Adjunct professor, MD, Gynecologic oncologist

- Docent,
Department of Clinical Medicine (Faculty of Medicine)
- ,
Obstetrics and Gynaecology (Department of Clinical Medicine)

mijohy@utu.fi

: https://orcid.org/0000-0002-0854-7225(external)

gynaecologic oncology; ovarian cancer

https://sites.utu.fi/ovariancancer/ https://www.deciderproject.eu

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Association of clinical and laboratory variables with risk of venous thromboembolism in high-grade serous ovarian cancer (2025)
- International Journal of Gynecological Cancer
Peippo, Maija H.; Perkonoja, Katariina; Isoviita, Veli-Matti; Hynninen, Johanna; Lassila, Riitta; Carpén, Olli
MUC1 and glycan probing of CA19-9 captured biomarkers from cyst fluids and serum provides enhanced recognition of ovarian cancer (2025)
- Scientific Reports
Afrin Ruma, Shamima; Vinod, Rufus; Jain, Shruti; Huhtinen, Kaisa; Hynninen, Johanna; Leivo, Janne; Pettersson, Kim; Sundfeldt, Karin; Gidwani, Kamlesh
A synthetic lethal dependency on casein kinase 2 in response to replication-perturbing therapeutics in RB1-deficient cancer cells (2024)
- Science Advances
Bulanova, Daria; Akimov, Yevhen; Senkowski, Wojciech; Oikkonen, Jaana; Gall-Mas, Laura; Timonen, Sanna; Elmadani, Manar; Hynninen, Johanna; Hautaniemi, Sampsa; Aittokallio, Tero; Wennerberg, Krister
Bexmarilimab Activates Human Tumor-Associated Macrophages to Support Adaptive Immune Responses in Interferon-Poor Immune Microenvironments (2024)
- Cancer Immunology Research
Rannikko Jenna H., Bono Petri, Hynninen Johanna, Hollmén Maija
Chemotherapy induces myeloid-driven spatially confined T cell exhaustion in ovarian cancer (2024)
- Cancer Cell
Launonen, Inga-Maria; Niemiec, Iga; Hincapié-Otero, María; Erkan, Pekcan Erdogan; Junquera, Ada; Afenteva, Daria; Falco, Matias M.; Liang, Zhihan; Salko, Matilda; Chamchougia, Foteini; Szabo, Angela; Perez-Villatoro, Fernando; Li, Yilin; Micoli, Giulia; Nagaraj, Ashwini; Haltia, Ulla-Maija; Kahelin, Essi; Oikkonen, Jaana; Hynninen, Johanna; Virtanen, Anni; Nirmal, Ajit J.; Vallius, Tuulia; Hautaniemi, Sampsa; Sorger, Peter K.; Vähärautio, Anna; Färkkilä, Anniina
Deciphering cancer genomes with GenomeSpy : a grammar-based visualization toolkit (2024)
- GigaScience
Lavikka, Kari; Oikkonen, Jaana; Li, Yilin; Muranen, Taru; Micoli, Giulia; Marchi, Giovanni; Lahtinen, Alexandra; Huhtinen, Kaisa; Lehtonen, Rainer; Hietanen, Sakari; Hynninen, Johanna; Virtanen, Anni; Hautaniemi, Sampsa
Extensive mutational ctDNA profiles reflect High-grade serous cancer tumors and reveal emerging mutations at recurrence (2024)
- Translational Oncology
Marchi Giovanni, Rajavuori Anna, Nguyen Mai T. N., Huhtinen Kaisa, Oksa Sinikka, Hietanen Sakari, Hautaniemi Sampsa, Hynninen Johanna, Oikkonen Jaana
Genome-wide quantification of copy-number aberration impact on gene expression in ovarian high-grade serous carcinoma (2024)
- BMC Cancer
Jamalzadeh Sanaz, Dai Jun, Lavikka Kari, Li Yilin, Jiang Jing, Huhtinen Kaisa, Virtanen Anni, Oikkonen Jaana, Hietanen Sakari, Hynninen Johanna, Vähärautio Anna, Häkkinen Antti, Hautaniemi Sampsa
HRD related signature 3 predicts clinical outcome in advanced tubo-ovarian high-grade serous carcinoma (2024)
- Gynecologic Oncology
Koskela Heidi, Li Yilin, Joutsiniemi Titta, Muranen Taru, Isoviita Veli-Matti, Huhtinen Kaisa, Micoli Giulia, Lavikka Kari, Marchi Giovanni, Hietanen Sakari, Virtanen Anni, Hautaniemi Sampsa, Oikkonen Jaana, Hynninen Johanna
Is it safe to operate selected low-risk endometrial cancer patients in secondary hospitals? (2024)
- EJSO - European Journal of Surgical Oncology
Narva Sara, Polo-Kantola Päivi, Oksa Sinikka, Kallio Johanna, Huvila Jutta, Rissanen Tiia, Hynninen Johanna, Hietanen Sakari, Joutsiniemi Titta
Kohdunrungon syövän diagnostiikka (2024) Syöpäsairaudet Puistola, Ulla; Mäenpää, Johanna; Staff, Synnöve; Hynninen, Johanna
Kohdunrungon syövän hoito (2024) Syöpäsairaudet Puistola, Ulla; Mäenpää, Johanna; Lindholm, Paula; Staff, Synnöve; Hynninen, Johanna
Kohdunrungon syövän yleisyys, vaaratekijät ja esiasteet (2024) Syöpäsairaudet Puistola, Ulla; Mäenpää, Johanna; Staff, Synnöve; Hynninen, Johanna
Kohtusarkoomat (2024) Syöpäsairaudet Puistola, Ulla; Mäenpää, Johanna; Staff, Synnöve; Hynninen, Johanna
Locus-specific LINE-1 expression in clinical ovarian cancer specimens at the single-cell level (2024)
- Scientific Reports
Perkiö Anna, Pradhan Barun, Genc Fatih, Pirttikoski Anna, Pikkusaari Sanna, Erkan Erdogan Pekcan, Falco Matias Marin, Huhtinen Kaisa, Narva Sara, Hynninen Johanna, Kauppi Liisa, Vähärautio Anna
PIK3R1 fusion drives chemoresistance in ovarian cancer by activating ERK1/2 and inducing rod and ring-like structures (2024)
- Neoplasia
Rausio Heidi, Cervera Alejandra, Heuser Vanina D., West Gun, Oikkonen Jaana, Pianfetti Elena, Lovino Marta, Ficarra Elisa, Taimen Pekka, Hynninen Johanna, Lehtonen Rainer, Hautaniemi Sampsa, Carpén Olli, Huhtinen Kaisa
Trofoblastisairaudet (2024) Syöpäsairaudet Mäenpää, Johanna; Puistola, Ulla; Urpilainen, Elina; Hynninen, Johanna
Trofoblastisairaudet (2024) Syöpäsairaudet Mäenpää, Johanna; Puistola, Ulla; Urpilainen, Elina; Hynninen, Johanna
A platform for efficient establishment and drug-response profiling of high-grade serous ovarian cancer organoids (2023)
- Developmental Cell
Senkowski Wojciech., Gall-Mas Laura, Falco Matias Marin, Li Yilin, Lavikka Kari, Kriegbaum Mette C., Oikkonen Jaana, Bulanova Daria, Pietras Elin J., Voßgröne Karolin, Chen Yan Jun., Erkan Erdogan Pekcan, Dai Jun, Lundgren Anastasia, Grønning Høg Mia Kristine, Larsen Ida Marie, Lamminen Tarja, Kaipio Katja, Huvila Jutta, Virtanen Anni, Engelholm Lars, Christiansen Pernille, Santoni-Rugiu Eric, Huhtinen Kaisa, Carpén Olli, Hynninen Johanna, Hautaniemi Sampsa, Vähärautio Anna, Wennerberg Krister
Circulating tumor DNA-based copy-number profiles enable monitoring treatment effects during therapy in high-grade serous carcinoma (2023)
- Biomedicine and Pharmacotherapy
Nguyen Mai TN, Rajavuori Anna, Huhtinen Kaisa, Hietanen Sakari, Hynninen Johanna, Oikkonen Jaana, Hautaniemi Sampsa