Johanna Hynninen
Adjunct professor, MD, Gynecologic oncologist
gynaecologic oncology; ovarian cancer
https://sites.utu.fi/ovariancancer/ https://www.deciderproject.eu
- Association of clinical and laboratory variables with risk of venous thromboembolism in high-grade serous ovarian cancer (2025)
- International Journal of Gynecological Cancer
Peippo, Maija H.; Perkonoja, Katariina; Isoviita, Veli-Matti; Hynninen, Johanna; Lassila, Riitta; Carpén, Olli
- Decoding the Genomic and Functional Landscape of Emerging Subtypes in Ovarian Cancer (2025) Micoli, Giulia; Lavikka, Kari; Li, Yilin; Pirttikoski, Anna; Afenteva, Daria; Senkowski, Wojciech; Marchi, Giovanni; Vähärautio, Anna; Muranen, Taru A.; Joutsiniemi, Titta; Hietanen, Sakari; Virtanen, Anni; Wennerberg, Krister; Hynninen, Johanna; Oikkonen, Jaana; Hautaniemi, Sampsa
- Drug target proteome profiling identifies HES1-driven mitotic catastrophe in ovarian serous carcinoma (2025)
- Biomedicine and Pharmacotherapy
Bao, Jie; Pikkusaari, Sanna; Dai, Jun; Leppiniemi, Samuel; Huang, Wenjun; Yang, Weiming; Anil, Anu; Pääkkönen, Mirva; Lei, Chuqi; Mendoza-Ortiz, Eva Daniela; Karagöz, Ezgi; Eriksson, Johanna; Li, Min; Hynninen, Johanna; Kauko, Otto; Färkkilä, Anniina; Vähärautio, Anna; Hautaniemi, Sampsa; Kauppi, Liisa; Tang, Jing
- MUC1 and glycan probing of CA19-9 captured biomarkers from cyst fluids and serum provides enhanced recognition of ovarian cancer (2025) Afrin Ruma, Shamima; Vinod, Rufus; Jain, Shruti; Huhtinen, Kaisa; Hynninen, Johanna; Leivo, Janne; Pettersson, Kim; Sundfeldt, Karin; Gidwani, Kamlesh
- Multi-omics analysis reveals the attenuation of the interferon pathway as a driver of chemo-refractory ovarian cancer (2025) Afenteva, Daria; Yu, Rong; Rajavuori, Anna; Salvadores, Marina; Launonen, Inga-Maria; Lavikka, Kari; Zhang, Kaiyang; Pirttikoski, Anna; Marchi, Giovanni; Jamalzadeh, Sanaz; Isoviita, Veli-Matti; Li, Yilin; Micoli, Giulia; Erkan, Erdogan Pekcan; Falco, Matias M.; Ungureanu, Daniela; Lahtinen, Alexandra; Oikkonen, Jaana; Hietanen, Sakari; Vähärautio, Anna; Sur, Inderpreet; Virtanen, Anni; Färkkilä, Anniina; Hynninen, Johanna; Muranen, Taru A.; Taipale, Jussi; Hautaniemi, Sampsa
- Novel glycovariant biomarkers of CA125 and CA15-3 and their diagnostic performance across histotypes of ovarian cancer: A multi-cohort study in Sweden and Finland (2025)
- European Journal of Obstetrics and Gynecology and Reproductive Biology
Roos Alexander, Hanna; Jain, Shruti; Gidwani, Kamlesh; Ulfenborg, Benjamin; Ottander, Ulrika; Lundin, Eva; Hynninen, Johanna; Afrin Ruma, Shamima; Huhtinen, Kaisa; Sundfeldt, Karin; Pettersson, Kim; Idahl, Annika
- A synthetic lethal dependency on casein kinase 2 in response to replication-perturbing therapeutics in RB1-deficient cancer cells (2024) Bulanova, Daria; Akimov, Yevhen; Senkowski, Wojciech; Oikkonen, Jaana; Gall-Mas, Laura; Timonen, Sanna; Elmadani, Manar; Hynninen, Johanna; Hautaniemi, Sampsa; Aittokallio, Tero; Wennerberg, Krister
- Bexmarilimab Activates Human Tumor-Associated Macrophages to Support Adaptive Immune Responses in Interferon-Poor Immune Microenvironments (2024)
- Cancer Immunology Research
Rannikko Jenna H., Bono Petri, Hynninen Johanna, Hollmén Maija
- Chemotherapy induces myeloid-driven spatially confined T cell exhaustion in ovarian cancer (2024) Launonen, Inga-Maria; Niemiec, Iga; Hincapié-Otero, María; Erkan, Pekcan Erdogan; Junquera, Ada; Afenteva, Daria; Falco, Matias M.; Liang, Zhihan; Salko, Matilda; Chamchougia, Foteini; Szabo, Angela; Perez-Villatoro, Fernando; Li, Yilin; Micoli, Giulia; Nagaraj, Ashwini; Haltia, Ulla-Maija; Kahelin, Essi; Oikkonen, Jaana; Hynninen, Johanna; Virtanen, Anni; Nirmal, Ajit J.; Vallius, Tuulia; Hautaniemi, Sampsa; Sorger, Peter K.; Vähärautio, Anna; Färkkilä, Anniina
- Deciphering cancer genomes with GenomeSpy : a grammar-based visualization toolkit (2024) Lavikka, Kari; Oikkonen, Jaana; Li, Yilin; Muranen, Taru; Micoli, Giulia; Marchi, Giovanni; Lahtinen, Alexandra; Huhtinen, Kaisa; Lehtonen, Rainer; Hietanen, Sakari; Hynninen, Johanna; Virtanen, Anni; Hautaniemi, Sampsa
- Extensive mutational ctDNA profiles reflect High-grade serous cancer tumors and reveal emerging mutations at recurrence (2024) Marchi Giovanni, Rajavuori Anna, Nguyen Mai T. N., Huhtinen Kaisa, Oksa Sinikka, Hietanen Sakari, Hautaniemi Sampsa, Hynninen Johanna, Oikkonen Jaana
- Genome-wide quantification of copy-number aberration impact on gene expression in ovarian high-grade serous carcinoma (2024) Jamalzadeh Sanaz, Dai Jun, Lavikka Kari, Li Yilin, Jiang Jing, Huhtinen Kaisa, Virtanen Anni, Oikkonen Jaana, Hietanen Sakari, Hynninen Johanna, Vähärautio Anna, Häkkinen Antti, Hautaniemi Sampsa
- HRD related signature 3 predicts clinical outcome in advanced tubo-ovarian high-grade serous carcinoma (2024) Koskela Heidi, Li Yilin, Joutsiniemi Titta, Muranen Taru, Isoviita Veli-Matti, Huhtinen Kaisa, Micoli Giulia, Lavikka Kari, Marchi Giovanni, Hietanen Sakari, Virtanen Anni, Hautaniemi Sampsa, Oikkonen Jaana, Hynninen Johanna
- Is it safe to operate selected low-risk endometrial cancer patients in secondary hospitals? (2024)
- EJSO - European Journal of Surgical Oncology
Narva Sara, Polo-Kantola Päivi, Oksa Sinikka, Kallio Johanna, Huvila Jutta, Rissanen Tiia, Hynninen Johanna, Hietanen Sakari, Joutsiniemi Titta
- Kohdunrungon syövän diagnostiikka (2024) Syöpäsairaudet Puistola, Ulla; Mäenpää, Johanna; Staff, Synnöve; Hynninen, Johanna
- Kohdunrungon syövän hoito (2024) Syöpäsairaudet Puistola, Ulla; Mäenpää, Johanna; Lindholm, Paula; Staff, Synnöve; Hynninen, Johanna
- Kohdunrungon syövän yleisyys, vaaratekijät ja esiasteet (2024) Syöpäsairaudet Puistola, Ulla; Mäenpää, Johanna; Staff, Synnöve; Hynninen, Johanna
- Kohtusarkoomat (2024) Syöpäsairaudet Puistola, Ulla; Mäenpää, Johanna; Staff, Synnöve; Hynninen, Johanna
- Locus-specific LINE-1 expression in clinical ovarian cancer specimens at the single-cell level (2024) Perkiö Anna, Pradhan Barun, Genc Fatih, Pirttikoski Anna, Pikkusaari Sanna, Erkan Erdogan Pekcan, Falco Matias Marin, Huhtinen Kaisa, Narva Sara, Hynninen Johanna, Kauppi Liisa, Vähärautio Anna
- PIK3R1 fusion drives chemoresistance in ovarian cancer by activating ERK1/2 and inducing rod and ring-like structures (2024) Rausio Heidi, Cervera Alejandra, Heuser Vanina D., West Gun, Oikkonen Jaana, Pianfetti Elena, Lovino Marta, Ficarra Elisa, Taimen Pekka, Hynninen Johanna, Lehtonen Rainer, Hautaniemi Sampsa, Carpén Olli, Huhtinen Kaisa
