Kari Kopra - UTU Research Portal - UTU Research Portal

Kari Kopra

- Docent,
Department of Chemistry (Faculty of Science)
- University Teacher,
Pharmaseutical Chemistry (Department of Chemistry)

khkopr@utu.fi

: https://orcid.org/0000-0001-7585-6020

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High-throughput amenable fluorescence-assays to screen for calmodulin-inhibitors (2019)
- Analytical Biochemistry
Manoharan G.B., Kopra K., Eskonen V., Härmä H., Abankwa D.
Homogeneous peptide-break assay for luminescent detection of enzymatic protein post-translational modification activity utilizing charged peptides (2019)
- Analytica Chimica Acta
Kopra K., Tong-Ochoa N., Laine M., Eskonen V., Koskinen P., Härmä H.
Peptic Fluorescent "Signal-On" and "Signal-Off" Sensors Utilized for the Detection Protein Post-Translational Modifications (2019)
- ACS Omega
Kopra K, Eskonen V, Seppala T, Jakovleva J, Huttunen R, Harma H
QTR-FRET: Efficient background reduction technology in time-resolved förster resonance energy transfer assays (2019)
- Analytica Chimica Acta
Markku Syrjänpää, Emmiliisa Vuorinen, Sakari Kulmala, Qi Wang, Harri Härmä, Kari Kopra
Thermal Dissociation Assay for Time-Resolved Fluorescence Detection of Protein Post-Translational Modifications (2019)
- ACS Omega
Ville Eskonen, Natalia Tong-Ochoa, Salla Valtonen, Kari Kopra, Harri Härmä
Label-Free Time-Gated Luminescent Detection Method for the Nucleotides with Varying Phosphate Content (2018)
- Sensors
Kopra K., Seppälä T., Rabara D., Abreu-Blanco M., Kulmala S., Holderfield M., Härmä H.
Toward universal protein post-translational modification detection in high throughput format (2018)
- Chemical Communications
Harri Härmä, Natalia Tong-Ochoa, Arjan J. van Adrichem, Ilian Jelesarov, Krister Wennerberg, Kari Kopra
High-Throughput Dual Screening Method for Ras Activities and Inhibitors (2017)
- Analytical Chemistry
Kari Kopra, Arjan J. van Adrichem, Outi M. H. Salo-Ahen, Juha Peltonen, Krister Wennerberg, Harri Härmä
From Unspecific Quenching to Specific Signaling: Functional GTPase Assays Utilizing Quenching Resonance Energy Transfer (QRET) Technology (2015) Kopra Kari
GTP-Specific Fab Fragment-Based GTPase Activity Assay (2015)
- Analytical Chemistry
Kopra K, Rozwandowicz-Jansen A, Syrjanpaa M, Blazevits O, Ligabue A, Veltel S, Lamminmaki U, Abankwa D, Harma H
Homogeneous single-label tyrosine kinase activity assay for high throughput screening (2015)
- Analytica Chimica Acta
Natalia Tong-Ochoa, Kari Kopra, Markku Syrjänpää, Nicolas Legrand, Harri Härmä
Quenching resonance energy transfer (QRET): a single-label technique for inhibitor screening and interaction studies (2015)
- New Biotechnology
Kopra Kari, Härmä Harri
Specific cancer-associated mutations in the switch III region of Ras increase tumorigenicity by nanocluster augmentation (2015)
- eLife
Maja Šolman, Alessio Ligabue, Olga Blaževitš, Alok Jaiswal, Yong Zhou, Hong Liang, Benoit Lectez, Kari Kopra, Camilo Guzmán, Harri Härmä, John F Hancock, Tero Aittokallio, Daniel Abankwa
Time-resolved fluorescence-based assay for rapid detection of Escherichia coli. (2015)
- Analytical Biochemistry
Janne Kulpakko, Kari Kopra, Pekka Hänninen
A homogeneous quenching resonance energy transfer assay for H-Ras activation cycle monitoring and inhibitor screening (2014)
- New Biotechnology
Kari Kopra, Arjan van Aldrichem, Markku Syrjänpää, Stefan Veltel, Pekka Hänninen, Daniel Abankwa, Urpo Lamminmäki, Harri Härmä
A homogeneous quenching resonance energy transfer assay for the kinetic analysis of the GTPase nucleotide exchange reaction. (2014)
- Analytical and Bioanalytical Chemistry
Kari Kopra, Alessio Ligabue, Qi Wang, Markku Syrjänpää, Olga Blaževitš,
Stefan Veltel, Arjan J. van Adrichem, Pekka Hänninen, Daniel Abankwa, Harri Härmä
Non-competitive aptamer-based quenching resonance energy transfer assay for homogeneous growth factor quantification (2014)
- Analyst
Kari Kopra, Markku Syrjänpää, Pekka Hänninen, Harri Härmä
A homogeneous single-label quenching resonance energy transfer assay for a delta-opioid receptor-ligand using intact cells (2013)
- Analyst
Kopra K, Shweta, Martikkala E, Hanninen P, Petaja-Repo U, Harma H
Aptamer-directed lanthanide chelate self-assembly for rapid thrombin detection (2013)
- Analyst
Päkkilä H, Blom S, Kopra K, Soukka T
Multiparametric Homogeneous Method for Identification of Ligand Binding to G Protein-Coupled Receptors: Receptor-Ligand Binding and beta-Arrestin Assay (2013)
- Analytical Chemistry
Kopra K, Kainulainen M, Mikkonen P, Rozwandowicz-Jansen A, Hanninen P, Harma H