Kari Kopra - UTU Research Portal - UTU Research Portal

Kari Kopra

- Docent,
Department of Chemistry (Faculty of Science)
- University Teacher,
Pharmaseutical Chemistry (Department of Chemistry)

khkopr@utu.fi

: https://orcid.org/0000-0001-7585-6020

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Nanomolar Protein-Protein Interaction Monitoring with a Label-Free Protein-Probe Technique (2020)
- Analytical Chemistry
Valtonen S, Vuorinen E, Kariniemi T, Eskonen V, Le Quesne J, Bushell M, Härmä H, Kopra K
Sensitive Label-Free Thermal Stability Assay for Protein Denaturation and Protein-Ligand Interaction Studies (2020)
- Analytical Chemistry
Emmiliisa Vuorinen, Salla Valtonen, Ville Eskonen, Taru Kariniemi, Jelena Jakovleva, Kari Kopra, Harri Härmä
(2020)
- Analytical ChemistryAnalytical Chemistry
Eskonen V, Tong-Ochoa N, Mattsson L, Miettinen M, Lastusaari M, Pulliainen AT, Kopra K, Härmä H
(2019)
- Genome Biology
Ania Wilczynska, Sarah L. Gillen, Tobias Schmidt, Hedda A. Meijer, Rebekah Jukes-Jones, Claudia Langlais, Kari Kopra, Wei-Ting Lu, Jack D. Godfrey, Benjamin R. Hawley, Kelly Hodge, Sara Zanivan, Kelvin Cain, John Le Quesne, Martin Bushell
(2019)
- Analytical BiochemistryAnalytical Chemistry
Manoharan G.B., Kopra K., Eskonen V., Härmä H., Abankwa D.
2019
- Analytica Chimica ActaAnalytica Chimica Acta
Kopra K., Tong-Ochoa N., Laine M., Eskonen V., Koskinen P., Härmä H.
(2019)
- ACS OmegaNew Biotechnology
Kopra K, Eskonen V, Seppala T, Jakovleva J, Huttunen R, Harma H
QTR-FRET: Efficient background reduction technology in time-resolved förster resonance energy transfer assays2019
- Analytica Chimica ActaeLife
Markku Syrjänpää, Emmiliisa Vuorinen, Sakari Kulmala, Qi Wang, Harri Härmä, Kari Kopra
Thermal Dissociation Assay for Time-Resolved Fluorescence Detection of Protein Post-Translational Modifications2019
- ACS Omega
Ville Eskonen, Natalia Tong-Ochoa, Salla Valtonen, Kari Kopra, Harri Härmä
Label-Free Time-Gated Luminescent Detection Method for the Nucleotides with Varying Phosphate Content2018
- Sensors
Kopra K., Seppälä T., Rabara D., Abreu-Blanco M., Kulmala S., Holderfield M., Härmä H.
Toward universal protein post-translational modification detection in high throughput format (2018)
- Chemical CommunicationsAnalytical and Bioanalytical Chemistry
Harri Härmä, Natalia Tong-Ochoa, Arjan J. van Adrichem, Ilian Jelesarov, Krister Wennerberg, Kari Kopra
High-Throughput Dual Screening Method for Ras Activities and Inhibitors (2017)
Kari Kopra, Arjan J. van Adrichem, Outi M. H. Salo-Ahen, Juha Peltonen, Krister Wennerberg, Harri Härmä
From Unspecific Quenching to Specific Signaling: Functional GTPase Assays Utilizing Quenching Resonance Energy Transfer (QRET) Technology (2015) Kopra Kari
GTP-Specific Fab Fragment-Based GTPase Activity Assay (2015)
Kopra K, Rozwandowicz-Jansen A, Syrjanpaa M, Blazevits O, Ligabue A, Veltel S, Lamminmaki U, Abankwa D, Harma H
Homogeneous single-label tyrosine kinase activity assay for high throughput screening (2015)
Natalia Tong-Ochoa, Kari Kopra, Markku Syrjänpää, Nicolas Legrand, Harri Härmä
Quenching resonance energy transfer (QRET): a single-label technique for inhibitor screening and interaction studies (2015)
Kopra Kari, Härmä Harri
Specific cancer-associated mutations in the switch III region of Ras increase tumorigenicity by nanocluster augmentation (2015)
Maja Šolman, Alessio Ligabue, Olga Blaževitš, Alok Jaiswal, Yong Zhou, Hong Liang, Benoit Lectez, Kari Kopra, Camilo Guzmán, Harri Härmä, John F Hancock, Tero Aittokallio, Daniel Abankwa
Time-resolved fluorescence-based assay for rapid detection of Escherichia coli. (2015)
- Analytical Biochemistry
Janne Kulpakko, Kari Kopra, Pekka Hänninen
A homogeneous quenching resonance energy transfer assay for H-Ras activation cycle monitoring and inhibitor screening (2014)
- New Biotechnology
Kari Kopra, Arjan van Aldrichem, Markku Syrjänpää, Stefan Veltel, Pekka Hänninen, Daniel Abankwa, Urpo Lamminmäki, Harri Härmä
A homogeneous quenching resonance energy transfer assay for the kinetic analysis of the GTPase nucleotide exchange reaction. (2014)
Kari Kopra, Alessio Ligabue, Qi Wang, Markku Syrjänpää, Olga Blaževitš,
Stefan Veltel, Arjan J. van Adrichem, Pekka Hänninen, Daniel Abankwa, Harri Härmä