Mikko Metsä-Ketelä
mianme@utu.fi +358 29 450 4786 +358 50 436 6523 Tykistökatu 6 Turku |
Natural products; Streptomyces; biosynthesis
http://abelab.utu.fi
Molecular Biology
Structural Biology
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- Ketosynthase III as a gateway to engineering the biosynthesis of antitumoral benastatin derivatives (2009)
- Journal of Biotechnology
- A nested gene in Streptomyces bacteria encodes a protein involved in quaternary complex formation (2008) Kallio P, Liu ZL, Mantsala P, Niemi J, Metsa-Ketela M
- Anthracycline biosynthesis: Genes, enzymes and mechanisms (2008)
- Topics in Current Chemistry
- Biosynthetic anthracycline variants (2008)
- Topics in Current Chemistry
- Characterization of the Alnumycin Gene Cluster Reveals Unusual Gene Products for Pyran Ring Formation and Dioxan Biosynthesis (2008)
- Chemistry and Biology
- Sequential action of two flavoenzymes, PgaE and PgaM, in angucycline biosynthesis: Chemoenzymatic synthesis of gaudimycin C (2008)
- Chemistry and Biology
- Artificial reconstruction of two cryptic anglucycline antibiotic Biosynthetic pathways (2007)
- ChemBioChem
- Crystal structures of two aromatic hydroxylases involved in the early tailoring steps of angucycline biosynthesis (2007)
- Journal of Molecular Biology
- Crystal structures of two aromatic hydroxylases involved in the early tailoring steps of angucycline biosynthesis (2007) Koskiniemi H, Metsa-Ketela M, Dobritzsch D, Kallio P, Korhonen H, Mantsala P, Schneider G, Niemi J
- Partial activation of a silent angucycline-type gene cluster from a rubromycin beta producing Streptomyces sp PGA64 (2004)
- Journal of Antibiotics
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