Mikko Metsä-Ketelä

- Professor,
Biochemistry (Department of Life Technologies)

mianme@utu.fi

+358 29 450 4786

+358 50 436 6523

Tykistökatu 6

Turku

ABE

Areas of expertise

Natural products; Streptomyces; biosynthesis

Research

http://abelab.utu.fi

Teaching

Molecular Biology

Structural Biology

Publications

8 of 9

Ketosynthase III as a gateway to engineering the biosynthesis of antitumoral benastatin derivatives (2009)
- Journal of Biotechnology
Xu ZL, Metsa-Ketela M, Hertweck C
(A1 Refereed original research article in a scientific journal)
A nested gene in Streptomyces bacteria encodes a protein involved in quaternary complex formation (2008) Kallio P, Liu ZL, Mantsala P, Niemi J, Metsa-Ketela M
(A1 Refereed original research article in a scientific journal)
Anthracycline biosynthesis: Genes, enzymes and mechanisms (2008)
- Topics in Current Chemistry
Metsa-Ketela M, Niemi J, Mantsala P, Schneider G
(C1 Refereed scientific book)
Biosynthetic anthracycline variants (2008)
- Topics in Current Chemistry
Niemi J, Metsa-Ketela M, Schneider G, Mantsala P
(C1 Refereed scientific book)
Characterization of the Alnumycin Gene Cluster Reveals Unusual Gene Products for Pyran Ring Formation and Dioxan Biosynthesis (2008)
- Chemistry and Biology
Oja T, Palmu K, Lehmussola H, Lepparanta O, Hannikainen K, Niemi J, Mantsala P, Metsa-Ketela M
(A1 Refereed original research article in a scientific journal)
Sequential action of two flavoenzymes, PgaE and PgaM, in angucycline biosynthesis: Chemoenzymatic synthesis of gaudimycin C (2008)
- Chemistry and Biology
Kallio P, Liu ZL, Mantsala P, Niemi J, Metsa-Ketela M
(A1 Refereed original research article in a scientific journal)
Artificial reconstruction of two cryptic anglucycline antibiotic Biosynthetic pathways (2007)
- ChemBioChem
Palmu K, Ishida K, Mantsala P, Hertweck C, Metsa-Ketela M
(A1 Refereed original research article in a scientific journal)
Crystal structures of two aromatic hydroxylases involved in the early tailoring steps of angucycline biosynthesis (2007)
- Journal of Molecular Biology
Koskiniemi H, Metsa-Ketela M, Dobritzsch D, Kallio P, Korhonen H, Mantsala P, Schneider G, Niemi J
(A1 Refereed original research article in a scientific journal)
Crystal structures of two aromatic hydroxylases involved in the early tailoring steps of angucycline biosynthesis (2007) Koskiniemi H, Metsa-Ketela M, Dobritzsch D, Kallio P, Korhonen H, Mantsala P, Schneider G, Niemi J
(A1 Refereed original research article in a scientific journal)
Partial activation of a silent angucycline-type gene cluster from a rubromycin beta producing Streptomyces sp PGA64 (2004)
- Journal of Antibiotics
Metsa-Ketela M, Ylihonko K, Mantsala P
(A1 Refereed original research article in a scientific journal)