Mikko Metsä-Ketelä

- Professor,
Biochemistry (Department of Life Technologies)

mianme@utu.fi

+358 29 450 4786

+358 50 436 6523

Tykistökatu 6

Turku

ABE

Areas of expertise

Natural products; Streptomyces; biosynthesis

Research

http://abelab.utu.fi

Teaching

Molecular Biology

Structural Biology

Publications

7 of 9

Biosynthetic pathway toward carbohydrate-like moieties of alnumycins contains unusual steps for C-C bond formation and cleavage (2012)
- Proceedings of the National Academy of Sciences of the United States of America
Oja T, Klika KD, Appassamy L, Sinkkonen J, Mäntsälä P, Niemi J, Metsä-Ketelä M
(A1 Refereed original research article in a scientific journal)
Characterization of the Two-Component Monooxygenase System AlnT/AlnH Reveals Early Timing of Quinone Formation in Alnumycin Biosynthesis (2012)
- Journal of Bacteriology
Grocholski T, Oja T, Humphrey L, Mäntsälä P, Niemi J, Metsä-Ketelä M
(A1 Refereed original research article in a scientific journal)
Crystal structure of the glycosyltransferase SnogD from the biosynthetic pathway of nogalamycin in Streptomyces nogalater (2012)
- FEBS Journal
Claesson M, Siitonen V, Dobritzsch D, Metsa-Ketela M, Schneider G
(A1 Refereed original research article in a scientific journal)
Discovery of a Two-Component Monooxygenase SnoaW/SnoaL2 Involved in Nogalamycin Biosynthesis (2012)
- Chemistry and Biology
Siitonen V, Blauenburg B, Kallio P, Mantsala P, Metsa-Ketela M
(A1 Refereed original research article in a scientific journal)
Epimers vs. inverse epimers: the C-1 configuration in alnumycin A1 (2012)
- RSC Advances
Tahtinen P, Oja T, Dreiack N, Mantsala P, Niemi J, Metsa-Ketela M, Klika KD
(A1 Refereed original research article in a scientific journal)
Formation of 5-Hydroxy-3-methoxy-1,4-naphthoquinone and 8-Hydroxy-4-methoxy-1,2-naphthoquinone from Juglone (2012) Bastian Blunenburg, Mikko Metsä-Ketelä, Karel D Klika
(A1 Refereed original research article in a scientific journal)
Identification of Late-Stage Glycosylation Steps in the Biosynthetic Pathway of the Anthracycline Nogalamycin (2012)
- ChemBioChem
Siitonen V, Claesson M, Patrikainen P, Aromaa M, Mantsala P, Schneider G, Metsa-Ketela M
(A1 Refereed original research article in a scientific journal)
Tailoring Enzymes Involved in the Biosynthesis of Angucyclines Contain Latent Context-Dependent Catalytic Activities (2012)
- Chemistry and Biology
Patrikainen P, Kallio P, Fan KQ, Klika KD, Shaaban KA, Mantsala P, Rohr J, Yang KQ, Niemi J, Metsa-Ketela M
(A1 Refereed original research article in a scientific journal)
The potential of VCD to resolve the epimer vs. inverse epimer quandary (2012)
- Computational and Theoretical Chemistry
Klika KD, Tahtinen P, Mantsala P, Niemi J, Metsa-Ketela M
(A1 Refereed original research article in a scientific journal)
Flavoprotein Hydroxylase PgaE Catalyzes Two Consecutive Oxygen-Dependent Tailoring Reactions in Angucycline Biosynthesis (2011)
- Biochemistry
Kallio P, Patrikainen P, Suomela JP, Mantsala P, Metsa-Ketela M, Niemi J
(A1 Refereed original research article in a scientific journal)