Vilja Siitonen
PhD (FT)
vksiit@utu.fi Tykistökatu 6 Turku : 6108 : https://orcid.org/0000-0002-1444-2622 |
Molecular biology; Protein biology; Bioactive small metabolites; Microbiology; Fermentation; Biotransformation, HPLC, MS, NMR, GC
Photosynthetic Microbes group
Senior Researcher, Photosynthetic Microbes -research group (www.utu.fi/photo-microbes) (2025–
Postdoctoral Researcher, Photosynthetic Microbes -research group (2020–2025)
Postdoctoral Researcher, ABE Lab – Antibiotic Biosynthetic Engineering -research group (https://abelab.utu.fi) (2017–2020)
Doctoral student, ABE Lab – Antibiotic Biosynthetic Engineering -research group (2011–2016)
Research assistant, ABE Lab – Antibiotic Biosynthetic Engineering -research group (2009–2010)
Summer trainee, University of Salzburg (https://www.plus.ac.at/) (2007)
My research in the Photosynthetic Microbes -research group focuses on utilizing green algae and cyanobacteria as biocatalysts or cell factories.
My previous research in the ABE -research group focused on soil bacteria, their fermentation, genetic modification, and the structural analysis of the compounds they produce, as well as studying the functions of proteins involved in antibiotic biosynthesis.
I have taught some parts on these courses:
Photosynthetic Biotechnologies (DIBT0608-3001) (2025)
Applied Photosynthesis Research - Theory (KABI4015) (2023, 2024)
Applied Photosynthesis Research - Practical (KABI4016-3002) (2021, 2022)
Harjoitustyö biokemian tutkimusryhmässä I/II (BKEM1028/1029) (2011–2019, 8 x 1 month)
Molekyylibiologian harjoitustyöt (BKEM1010) (2011)
I have supervised theses at different levels of studies.
I have studied university pedagogy 10 ECTS.
- ActVI-ORFA directs metabolic flux towards actinorhodin by preventing intermediate degradation (2024)
- PLoS ONE
- Employing photocurable biopolymers to engineer photosynthetic 3D-printed living materials for production of chemicals (2024)
- Green Chemistry
- Mechanism of Two-Component Mono-Oxygenases Involved in Anthracycline 1-Hydroxylation (2024)
- ACS Catalysis
- Sucrose as an electron source for cofactor regeneration in recombinant Escherichia coli expressing invertase and a Baeyer Villiger monooxygenase (2024)
- Microbial Cell Factories
- Bakteerien avulla antibiootteja mikrobi- ja syöpälääkkeiksi (2023)
- Duodecim
- Bioinspired mechanically stable all-polysaccharide based scaffold for photosynthetic production (2023)
- Journal of Materials Chemistry. B
- Co-factor independent oxidases ncnN and actVA-3 are involved in the dimerization of benzoisochromanequinone antibiotics in naphthocyclinone and actinorhodin biosynthesis (2023)
- FEMS Microbiology Letters
- Engineered green alga Chlamydomonas reinhardtii as a whole-cell photosynthetic biocatalyst for stepwise photoproduction of H-2 and ε-caprolactone (2023)
- Green Chemistry
- Evolution-inspired engineering of anthracycline methyltransferases (2023)
- PNAS nexus
- Mapping Nanocellulose- and Alginate-Based Photosynthetic Cell Factory Scaffolds: Interlinking Porosity, Wet Strength, and Gas Exchange (2023)
- Biomacromolecules
- Photosynthetically produced sucrose by immobilized Synechocystis sp. PCC 6803 drives biotransformation in E. coli (2022)
- Biotechnology for Biofuels and Bioproducts
- Single cell mutant selection for metabolic engineering of actinomycetes (2022)
- Metabolic Engineering
- Biosynthesis of Diverse Type II Polyketide Core Structures in Streptomyces coelicolor M1152 (2021)
- ACS Synthetic Biology
- Differential regulation of undecylprodigiosin biosynthesis in the yeast-scavenging Streptomyces strain MBK6 (2021)
- FEMS Microbiology Letters
- Evolution‐Guided Engineering of Non‐Heme Iron Enzymes Involved in Nogalamycin Biosynthesis (2020)
- FEBS Journal
- Genotyping-Guided Discovery of Persiamycin A From Sponge-Associated Halophilic Streptomonospora sp. PA3 (2020)
- Frontiers in microbiology
- Structural characterization of three noncanonical NTF2-like superfamily proteins: implications for polyketide biosynthesis (2020)
- Acta Crystallographica Section F: Structural Biology Communications
- The Rieske Oxygenase SnoT Catalyzes 2''-Hydroxylation of L-Rhodosamine in Nogalamycin Biosynthesis (2020)
- ChemBioChem
- Enzymatic Synthesis of the C-glycosidic Moiety of Nogalamycin R (2018)
- ACS Chemical Biology
- Discovery of the Showdomycin Gene Cluster from Streptomyces showdoensis ATCC 15227 Yields Insight into the Biosynthetic Logic of C-Nucleoside Antibiotics (2017)
- ACS Chemical Biology
