PhD Harri Savilahti - UTU Research Portal

Harri Savilahti
PhD

- Professor,
Physiology and Genetics (Department of Biology)

harri.savilahti@utu.fi

+358 40 708 5795

Vesilinnantie 5

Turku

: https://orcid.org/https://orcid.org/0000-0002-6246-2572

Research page

Molecular genetics; DNA transposition technology;

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Probing the alpha-complementing domain of E-coli beta-galactosidase with use of an insertional pentapeptide mutagenesis strategy based on Mu in vitro DNA transposition (2004)
- Proteins
Poussu E, Vihinen M, Paulin L, Savilahti H
Structure-function analysis of PrsA reveals roles for the parvulin-like and flanking N- and C-terminal domains in protein folding and secretion in Bacillus subtilis (2004) Vitikainen M, Lappalainen I, Seppala R, Antelmann H, Boer H, Taira S, Savilahti H, Hecker M, Vihinen M, Sarvas M, Kontinen VP
A direct transposon insertion tool for modification and functional analysis of viral genomes (2003)
- Journal of Virology
Vilen H, Aalto JM, Kassinen A, Paulin L, Savilahti H
Transposon mutagenesis of the phage phi YeO3-12 (2003)
- Advances in Experimental Medicine and Biology
The Genus Yersinia Kiljunen S, Vilen H, Savilahti H, Skurnik M
Use of intein-directed peptide biosynthesis to improve serum stability and bioactivity of a gelatinase inhibitory peptide (2003)
- Combinatorial Chemistry and High Throughput Screening
Bjorklund M, Valtanen H, Savilahti H, Koivunen E
DNA transposition of bacteriophage Mu - A quantitative analysis of target site selection in vitro (2002) Haapa-Paananen S, Rita H, Savilahti H
Efficient insertion mutagenesis strategy for bacterial genomes involving electroporation of in vitro-assembled DNA transposition complexes of bacteriophage Mu (2002)
- Applied and Environmental Microbiology
Lamberg A, Nieminen S, Qiao MQ, Savilahti H
Functional Genomics on Potato virus A: Virus genome-wide map of sites essential for virus propagation (2002) Kekarainen T, Savilahti H, Valkonen JPT
Construction of gene-targeting vectors: A rapid Mu in vitro DNA transposition-based strategy generating null, potentially hypomorphic, and conditional alleles (2001)
- Transgenic Research
Vilen H, Eerikäinen S, Tornberg J, Airaksinen MS, Savilahti H
Functional characterization of the human immunodeficiency virus type 1 genome by genetic footprinting (2000)
- Journal of Virology
Laurent LC, Olsen MN, Crowley RA, Savilahti H, Brown PO
Neuronal K+/Cl- cotransporter: Initial analysis of KCC2-deficient mice (2000)
- European Journal of Neuroscience
Tornberg J, Rivera C, Vilen H, Savilahti H, Kaila K, Saarma M, Airaksinen MS
An efficient and accurate integration of mini-Mu transposons in vitro: a general methodology for functional genetic analysis and molecular biology applications (1999)
- Nucleic Acids Research
Haapa S, Taira S, Heikkinen E, Savilahti H
An efficient DNA sequencing strategy based on the bacteriophage Mu in vitro DNA transposition reaction (1999)
- Genome Research
Haapa S, Suomalainen S, Eerikainen S, Airaksinen M, Paulin L, Savilahti H
Mutational analysis of the Pseudomonas syringae pv. tomato hrpA gene encoding Hrp pilus subunit (1999)
- Molecular Microbiology
Taira S, Tuimala J, Roine E, Nurmiaho-Lassila EL, Savilahti H, Romantschuk M
Retrotransposon BARE-1: expression of encoded proteins and formation of virus-like particles in barley cells (1999)
- Plant Journal
Jääskeläinen M, Mykkänen AH, Arna T, Vicient CM, Suoniemi A, Kalendar R, Savilahti H, Schulman AH
Mu transpositional recombination: Donor DNA cleavage and strand transfer in trans by the Mu transposase (1996)
- Cell
Savilahti H, Mizuuchi K
The wing of the enhancer-binding domain of Mu phage transposase is flexible and is essential for efficient transposition (1996)
- Proceedings of the National Academy of Sciences of the United States of America
Clubb RT, Mizuuchi M, Huth JR, Omichinski JG, Savilahti H, Mizuuchi K, Clore GM, Gronenborn AM
INVESTIGATIONS OF THE DNA-BINDING DOMAIN OF TRANSPOSASE - BACKBONE DYNAMICS AND MUTAGENESIS STUDIES (1995)
- Journal of Cellular Biochemistry
CLUBB R, HUTH J, OMICHINSKI JG, SAVILAHTI H, MIZUUCHI K, GRONENBORN AM, CLORE GM
THE PHAGE-MU TRANSPOSOSOME CORE - DNA REQUIREMENTS FOR ASSEMBLY AND FUNCTION (1995)
- EMBO Journal
SAVILAHTI H, RICE PA, MIZUUCHI K
A NOVEL CLASS OF WINGED HELIX-TURN-HELIX PROTEIN - THE DNA-BINDING DOMAIN OF MU TRANSPOSASE (1994)
- Structure
CLUBB RT, OMICHINSKI JG, SAVILAHTI H, MIZUUCHI K, GRONENBORN AM, CLORE GM