Harry Scheinin
MD
Anesthesiology and Intensive Care harry.scheinin@utu.fi ORCID identifier: https://orcid.org/0000-0002-1171-3511 |
Anesthesiology; Clinical Pharmacology; Neuroscience; Positron Emission Tomography
Harry Scheinin leads the Anesthesia Mechanisms Research Group at the University of Turku, Finland, and has studied the human neurobiology of anesthetic agents for 20 years. He has collaborated with Professor Antti Revonsuo since 2005.
We try to explore the neural correlates of human consciousness using, e.g., modern imaging methods. We aim to separate consciousness from responsiveness, connectedness from disconnection and to compare unconsciousness of physiological sleep with that induced by anesthetic agents. Finding new tools for the distinction of consciousness, connectedness and responsiveness would be groundbreaking and could represent a major leap forward in understanding human consciousness. The results could also help in developing new EEG-based methods to objectively measure consciousness and the depth of general anesthesia.
- Grey matter volume reduction and its association with brain-enriched blood biomarkers in out-of-hospital cardiac arrest survivors (2025)
- Scientific Reports
(A1 Refereed original research article in a scientific journal) - Neuroprotective Effects of Inhaled Xenon Gas on Brain Structural Gray Matter Changes After Out-of-Hospital Cardiac Arrest Evaluated by Morphometric Analysis: A Substudy of the Randomized Xe-Hypotheca Trial (2025)
- Neurocritical Care
(A1 Refereed original research article in a scientific journal) - A metabolic profile of xenon and metabolite associations with 6-month mortality after out-of-hospital cardiac arrest : A post-hoc study of the randomised Xe-Hypotheca trial (2024)
- PLoS ONE
(A1 Refereed original research article in a scientific journal) - Tendon graft through the coracoid tunnel versus under the coracoid for coracoclavicular/acromioclavicular reconstruction shows no difference in radiographic or patient-reported outcomes (2024)
- Archives of Orthopaedic and Trauma Surgery
(A1 Refereed original research article in a scientific journal) - The relationship of bispectral index values to conscious state: an analysis of two volunteer cohort studies (2024)
- British Journal of Anaesthesia
(A1 Refereed original research article in a scientific journal) - Comparison of the prognostic value of early-phase proton magnetic resonance spectroscopy and diffusion tensor imaging with serum neuron-specific enolase at 72 h in comatose survivors of out-of-hospital cardiac arrest-a substudy of the XeHypotheca trial (2023)
- Neuroradiology
(A1 Refereed original research article in a scientific journal) - Decreased Thalamic Activity Is a Correlate for Disconnectedness during Anesthesia with Propofol, Dexmedetomidine and Sevoflurane But Not S-Ketamine (2023)
- Journal of Neuroscience
(A1 Refereed original research article in a scientific journal) - Effects of dexmedetomidine on pharyngeal swallowing and esophageal motility-A double-blind randomized cross-over study in healthy volunteers (2023)
- Neurogastroenterology and Motility
(A1 Refereed original research article in a scientific journal) - Response to Letter to the Editor (2023)
- Neurogastroenterology and Motility
(B1 Non-refereed article in a scientific journal) - Subjective experiences during dexmedetomidine- or propofol-induced unresponsiveness and non-rapid eye movement sleep in healthy male subjects (2023)
- British Journal of Anaesthesia
(A1 Refereed original research article in a scientific journal)



